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中国防痨杂志 ›› 2004, Vol. 26 ›› Issue (4): 209-211.

• 论著 • 上一篇    下一篇

结核性与非结核炎性和恶性胸腔积液中γ-干扰素水平的比较

高同军1;王庆枫1;李有才1;陈希琛1;古淑香1;   

  1. 北京结核病胸部肿瘤研究所 北京 100710;
  • 出版日期:2004-04-10 发布日期:2004-11-03

Interferon-γ level in tuberculous and non-tuberculous inflammatory and malignant pleural effusions

Gao Tongjun,Wang Qingfeng,Li Youcai,et al.   

  1. Beijing TB & Thoracic Tumor Research Institute,Beijing 101149
  • Online:2004-04-10 Published:2004-11-03

摘要: 目的 检测结核性、非结核炎性及恶性胸腔积液中γ 干扰素的水平 ,探讨结核性与非结核性及恶性胸腔积液的γ 干扰素水平在鉴别诊断中的意义。方法 采用双抗体夹心ELISA法 ,对 5 1例结核性胸膜炎患者、30例恶性胸膜炎患者、2 0例非结核炎性胸膜炎患者胸液中的γ-干扰素水平进行检测。结果 3组γ-干扰素水平 (-x±s)结核性胸膜炎组为 553.33±70 .89pg ml,恶性胸膜炎组为 54.64± 36.37pg ml、非结核炎性胸膜炎组为 58.75±47.26 pg/ml。3组比较结核性胸膜炎组明显高于其他组 (P<0 .01)。结论 γ-干扰素检测可以作为结核性胸膜炎诊断的重要参考指标。

关键词: 胸腔积液, 结核病, γ-干扰素, 诊断

Abstract: Objective To detect interferon-γ level in tuberculous and non-tuberculous inflammatory and malignant pleural effusions,and explore its role for differentiation of diagnosis.Methods To detect interferon-γ level of 51 tuberculous pleurisy cases,30 malignant pleurisy cases and 20 non-tuberculous pleurisy cases by ELISA.Results There was a significant difference of interferon-γ levels different groups.The levels in tuberculous pleurisy group was 58.75±70.89 pg/ml.It is higher than that in other two groups (P<0.01).The levels in group of malignant pleurisy was 54.64±36.67 pg/ml and in the group of non-tuberculous pleurisy was 58.75±47.26 pg/ml.Conclusion The levels of interferon-γ could be an important reference indicator for diagnosis of tuberculous pleurisy.

Key words: Pleural effusions, Tuberculosis, Interferon-γ, Diagnosis