骨关节结核病灶结核菌L型状况的观察

中国防痨杂志 ›› 2004, Vol. 26 ›› Issue (4): 233-234.

骨关节结核病灶结核菌L型状况的观察

韩凤满；程宏；吴启秋；林羽；

北京结核病胸部肿瘤研究所北京 101149；

出版日期:2004-04-10 发布日期:2004-11-03

Study on L-form Mycobacterium bacilli in the lesions of osteoarticular tuberculosis cases

Han Fengman,Cheng Hong,Wu Qiqiu,et al.

Beijing Thoracic Tuberculosis and Tumor Institute,Beijing 101149

Online:2004-04-10 Published:2004-11-03

摘要/Abstract

摘要： 目的　探讨骨关节结核病灶中 ,结核菌L型的存在状况。方法样本均采自骨科住院病人的脓液、肉芽、干酪物等 ,经碱液处理后 ,分别进行直接涂片,并接种在罗氏培养基上、Bactec培养液及结核菌L型培养液中 ,以查找结核杆菌及结核菌L型。结果在 6 0例中 ,查到结核菌L型 11例(18.3% ),涂片阳性 9例 (15 % ) ,罗氏培养阳性 3例 (5 % ) ,快速培养阳性 12例 (2 0 % )。结论对骨关节结核病灶进行结核菌培养的同时,加做结核菌L型检查是十分必要的。

关键词: 分枝杆菌,结核, 结核菌L型, 结核,骨关节

Abstract: Objective To explore the exist of L-form Mycobacterium bacilli in the lesions of bone and joint tuberculosis.Methods After N-Acetyl-L-Cystein-Sodium Hydroxide (NALC-NaOH) decontamination and Z-N stains,the specimens collected from the lesions were inoculated in L-J culture media,Bactec 460 and L-form broth media for detecting the Mycobacterium bacilli and L-form of Mycobacterium bacilli.Results The L-form of Mycobacterium bacilli were found in the lesions of 11(18.3%) osteoarticular tuberculosis patients.The smear positive rate of smear and L-J culture positive were 9 cases (15%) and 3 cases (5%) respectively.The positive rate of Bactec 460 was 12 cases (20%).Conclusion It is necessary to make L-form Mycobacterium bacilli examination for retreatment tuberculosis patients.

Key words: Mycobacterium bacillus, L-form, Osteoarticular, Tuberculosis

韩凤满,程宏,吴启秋,林羽,. 骨关节结核病灶结核菌L型状况的观察[J]. 中国防痨杂志, 2004, 26(4): 233-234.

Han Fengman,Cheng Hong,Wu Qiqiu,et al.. Study on L-form Mycobacterium bacilli in the lesions of osteoarticular tuberculosis cases[J]. Chinese Journal of Antituberculosis, 2004, 26(4): 233-234.

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