门诊肺结核病人中筛查HIV感染病例的研究

中国防痨杂志 ›› 2008, Vol. 30 ›› Issue (5): 445-448.

门诊肺结核病人中筛查HIV感染病例的研究

黎国形¹；林定文²；陈春红¹；汤卓¹；李春坚³

1.南宁市第四人民医院南宁 530023；2.广西壮族自治区疾病预防控制中心南宁 530012；3.广西医科大学南宁 530021

出版日期:2008-05-10 发布日期:2011-11-03

Research on screening cases of double infection of TB and HIV in clinical TB patients

Li Guoxing¹, Lin Dingwen, Chen Chunhong,et al.

1. No. 4 People’s Hospital of Nanning, Nanning 530023,China

Online:2008-05-10 Published:2011-11-03

摘要/Abstract

摘要： 目的　调查门诊肺结核病人HIV感染情况,了解结核病与艾滋病双重感染的相关性。方法对2003—2006年门诊确诊的2074例肺结核病人进行HIV检测,访谈吸毒史、治游史、输血献血史。HIV阳性者进行CD₄和CD₈淋巴细胞计数和结核菌素（PPD）试验。结果肺结核与HIV/AIDS双重感染率为4.5%,其中男性为6.8%,女性为0.3%,平均增长速度24.3%,2040岁年龄组占95.7%。HIV感染者中97.9%来源吸毒,2.1%来源于夫妻性生活。吸毒肺结核病人中HIV阳性率49.2%,是单纯吸毒人群HIV感染率的3.4倍。CD₄/CD₈均小于1,平均为0.261。PPD试验阴性率为66.6%。结论广西南宁市结核病与艾滋病双重感染疫情快速蔓延,吸毒肺结核病人是筛查和防治HIV/AIDS的主要高危对象。

关键词: 结核,肺/并发症, HIV/AIDS

Abstract: Objective To research the HIV infection among clinical TB patients, in order to understand the relativity of TV and HIV double infection. Methods HIV test on 2074 clinically confirmed TB cases found from 2003 to 2006 were conducted, focus discussion on drug use history, frequent brothels, blood transfusion or donation history were interviewed. For the HIV positive cases, CD4 and CD8 Lymphatic Cell counts were done as well as PPD test. Results The double infection rate of TV and HIV/AIDS was 4.5%,and it was 6.8% among males and 0.3% among females. The average increase rate was 24.3%,and the age group from 20 to 40 was 95.7%. Among the HIV infected cases, 97.9% were infected through drug use, 2.1% were infected through sex among spouses. The HIV positive rate among the TB patients of drug users was 49.2%,which was 3.4 times of the other simple drug users. CD4/CD8 both below 1,and the average was 0.261. PPD test negative rate was 66.6%. Conclusion The TB and HIV double infection is spreading fast. TB patients who are also drug users should be the high risk group and target of the screening and HIV/AIDS control.

Key words: pulmonary tuberculosis/complication, HIV/AIDS

黎国形,林定文,陈春红,汤卓,李春坚. 门诊肺结核病人中筛查HIV感染病例的研究[J]. 中国防痨杂志, 2008, 30(5): 445-448.

Li Guoxing¹, Lin Dingwen, Chen Chunhong,et al.. Research on screening cases of double infection of TB and HIV in clinical TB patients[J]. Chinese Journal of Antituberculosis, 2008, 30(5): 445-448.

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[2]	刘凤仁,汤恒,殷继国,周沛林,叶建君,熊昌富,刘焰东,赵焕虎,叶临湘. HIV/AIDS人群中肺结核患者的治疗效果与细胞免疫的相关性研究[J]. 中国防痨杂志, 2008, 30(4): 311-315.