结核分枝杆菌早期分泌抗原靶6的研究进展及应用

中国防痨杂志 ›› 2011, Vol. 33 ›› Issue (12): 827-830.

结核分枝杆菌早期分泌抗原靶6的研究进展及应用

陶波山

536000 广西壮族自治区北海市结核病防治院检验科

收稿日期:2011-04-15 出版日期:2011-12-10 发布日期:2012-02-15
通信作者: 陶波山

The research advances and application of Mycobacterium tuberculosis early secreted protein ESAT-6

TAO Bo-shan

Received:2011-04-15 Online:2011-12-10 Published:2012-02-15
Contact: TAO Bo-shan

摘要/Abstract

摘要： 目前，结核病已是传染病的头号杀手。全世界近1/3的人感染Mtb，而且每年约有900万新发临床结核病患者及200～300万死亡患者。随着多耐药Mtb和HIV与Mtb双重感染的发生率增加，迫切需要研制新的疫苗和抗结核药物，以及可靠的早期诊断方法。Mtb早期分泌抗原靶6（6 kDa early secreted antigenic target protein, ESAT-6）是结核病疫苗和结核病诊断试剂的候选蛋白质之一。现对ESAT-6的基础研究概况及应用综述如下。

陶波山. 结核分枝杆菌早期分泌抗原靶6的研究进展及应用[J]. 中国防痨杂志, 2011, 33(12): 827-830.

TAO Bo-shan. The research advances and application of Mycobacterium tuberculosis early secreted protein ESAT-6[J]. Chinese Journal of Antituberculosis, 2011, 33(12): 827-830.

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