螺旋藻加转移因子辅助治疗复治肺结核疗效观察

中国防痨杂志 ›› 2005, Vol. 27 ›› Issue (1): 33-35.

螺旋藻加转移因子辅助治疗复治肺结核疗效观察

何连福；茶剑媛；吴世林；

云南省大理医学院附属医院大理 671000；

出版日期:2005-01-10 发布日期:2005-11-03

Observation of supplementary treatment effect of spirin and transfer factor for treating reteated pulmonary tuberculosis

He Lianfu, Cha Jianyuan,Wu Shilin.

Affiliated Hospital of DaLi Medical college,DaLi, 671000, China

Online:2005-01-10 Published:2005-11-03

摘要/Abstract

摘要： 目的　观察螺旋藻加转移因子辅助治疗复治肺结核疗效。方法将 192例涂阳复治患者随机分为治疗组 (100例)和对照组 (92例)。 2组化疗方案相同,治疗组在化疗同时加螺旋藻胶囊 3粒口服,3次/d；转移因子 3mg,皮下注射,2次 /周。结果 9月末痰菌阴转率,治疗组 92%,对照组73.9%(P＜0.01)；X线胸片病灶吸收好转率和空洞闭合率治疗组分别为 88%和 76%,对照组分别为 73.9%和 5 9.8%(P＜0.05)。治疗组不良反应发生率明显低于对照组 (分别为 6%和 26%,P＜0.01)。结论两药联合辅助治疗复治肺结核有效,并可降低抗结核药物不良反应的发生率。

关键词: 结核,肺/药物疗法, 螺旋藻, 转移因子

Abstract: Objective To observe the supplementary treatment effect for pulmonary tuberculosis treated of spirin and transfer factor.Methods One hundred and ninety two patients were divided into two groups: therapy group with 100 cases, control group with 92 cases. The therapy group received chemical therapy and three spirin capsules, three times a day, transfer factor 3mg, imjection(H) twice a week.Results At the end of 9 months, the sputum conversion rate was 92%(in therapy group), 73.9%(in control group), P＜0.01. The foci absorption was 88%(therapy group) and 76%(control group), Cavity cloce up was 73.9% (ther-apy group), 59.8%(control group),P＜0.05. The therapy group’s side effect rate (6%) was lower than that of control group(26%), P＜0.01. Conclusion The supplementary treatment effect of spirin and transfer factor for treating retreated pulmonary tuberculosis was obvious. Especially for reducing side effect of antituberculosis.

Key words: Pulmonary tuberculosis, Druy therapy, Spirin, Transfer fsctor

何连福,茶剑媛,吴世林,. 螺旋藻加转移因子辅助治疗复治肺结核疗效观察[J]. 中国防痨杂志, 2005, 27(1): 33-35.

He Lianfu, Cha Jianyuan,Wu Shilin.. Observation of supplementary treatment effect of spirin and transfer factor for treating reteated pulmonary tuberculosis[J]. Chinese Journal of Antituberculosis, 2005, 27(1): 33-35.