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中国防痨杂志 ›› 2002, Vol. 24 ›› Issue (4): 224-226.

• 论著 • 上一篇    下一篇

力克肺疾、氧氟沙星、卷曲霉素、丙硫异烟胺联合治疗耐多药肺结核的临床观察

姬宝军;   

  1. 河南省濮阳市结核病防治所 濮阳 457000;
  • 出版日期:2002-04-10 发布日期:2002-11-03

Clinical analysis of pasiniazid,ofloxacin,capreomycin and prothionamide in weating Multi-drug resistant tuberculosis

JI Bao jun.   

  1. Puyang Institute of Tuberculosis,Henan 457000
  • Online:2002-04-10 Published:2002-11-03

摘要: 目的 分析耐多药肺结核患者采用3LiOCTh/3LiThC3/6LiOTh方案治疗的临床效果。方法 1994年11月至1997年12月收治的54例同时耐INH、RFP的耐多药肺结核,采用3LiOCTh/3LiOThC3/6LiOTh方案治疗,疗程中每月进行痰结核菌检查和肝功能检查,疗程的3、6、12个月摄胸片。结果 54例完成疗程时痰菌阴转率87%,随访24个月的痰菌复发率为12.8%,肝功异常率1.9%,无一例因副反应停药。结论 对耐多药肺结核采用3LiOCTh/3LiOThC3/6LiOTh方案,治疗效果满意,药物副反应轻微,该方案值得在临床中推广应用。

关键词: 结核,肺/药物疗法, 耐多药

Abstract: Objective To explore the therapeutic effect of multi drug resistant tuberculosis cases treated with 3LiOCTh/3LiOThC 3/6LiOTh regimen.Methods 54 cases of multi drug resistant tuberculosis were treated with 3LiOCTh/3LiOThC 3/6LiOTh regimen from 1994 to 1997.The patients were examined with sputum smear and liver funtion very month,X ray in 3,6,12 month.Results When the treatment was completed,the sputum megative conversion rate was 87%.The sputum positive recurrent rate was 12.8% after 24 months follow up.The damage rate to the liver function was 1.9%.Conclu sion It is effective to treating multi frug resistant tuberculosis cases with 3LiOCTh/3LiOThC 3/6LiOTh regimen.The regimen is less adverse reaction and recommendable.

Key words: Tuberculosis,Pulmonary/drug therapy, Multidrug resistant