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中国防痨杂志 ›› 2001, Vol. 23 ›› Issue (5): 288-290.

• 论著 • 上一篇    下一篇

北京市大兴县1985~1999年新发涂阳病例化疗效果评价

申炳刚;   

  1. 北京市大兴区结核病防治所 北京 102600;
  • 出版日期:2001-05-10 发布日期:2001-11-03

Evaluation of the therapeutic results for new smear positive patients in Daxing County of Beijing during 1985~1999

SHEN Bing-gang.   

  1. Daxing County Tuberculosis Center,Beijing 102600
  • Online:2001-05-10 Published:2001-11-03

摘要: 目的 评价北京市大兴县15年新登记初治涂阳病例不住院监督化疗的效果。方法 对1985~1999年975例初治涂阳肺结核病例的治疗方案、监化、痰菌阴转、一年转归等资料进行总结分析。结果 1985~1989年使用12个月传统化疗方案,监化率为82%,疗程结束时痰菌阴转率为93%,队列分析治愈率为86%。1990年以后调整为HR(L)ZS(E)6个月短化方案,监化率在97%以上,阴转率在96%以上,队列分析治愈率在90%以上。结论 在地域广阔,人口居住分散,经济条件相对滞后的农村地区,把结核病控制工作纳入初级卫生保健,开展不住院监督短程化疗,严格执行DOTS策略,是当前结核病控制最有效的方法。

关键词: 结核,肺/预防和控制, 北京市

Abstract: Objective To evaluate the Results of newly registered initial treatment smear positive cases with fully supervised ambulatory chemotherapy.Methods 975 cases of initial treatment smear positive pulmonary tuberculosis registered during 1985~1999 were reviewed and analyzed including treatment regimens,supervised chemotherapy,sputum convert and cohort analysis etc..Results During 1985~1989,the 12 months treatment regimens were applied,the supervised chemotherapy rate was 82%,sputum conversion rate was 93% when the treatemtn courses completed,and cured rate was 86% by cohort analysis.Since 1990,six months short-course chemotherapy regimens,HR(L)ZS(E) were used,the supervised chemotherapy rate was over 97%,sputum conversion rate was over 96%,and cured rate was more than 90% by cohort analysis.Conclusion At present,strictly conducted DOTS strategy,especially fully supervised ambulatory chemotherapy is the best way for control tuberculosis at the population decentralized,relatively poor and extensive rural areas.

Key words: Tuberculosis,pulmonary/Prevention and Control, Beijing