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中国防痨杂志 ›› 2000, Vol. 22 ›› Issue (3): 154-156.

• 论著 • 上一篇    下一篇

抗结核药物引起的副作用604例临床分析

袁慧;谢丽娟;   

  1. 铁道部广州疗养院 广东广州 510095
  • 出版日期:2000-03-10 发布日期:2000-03-10

Clinical analysis of 604 cases on side effects of antituberculous agents

YUAN Hui,XIE Li-juan.   

  1. Guangzhou Sanatorium,Ministry of Railway.Guangdong 510095
  • Online:2000-03-10 Published:2000-03-10

摘要: 目的 了解抗结核药物副作用发生情况。方法 对1990~1998年住院肺结核患者1848例进行临床分析。结果 抗结核药物副作用604例 (32.7%),以肝损害、位听神经损害、血液学异常及胃肠反应为主 (82.1%),因副作用致终止治疗率14.6%。77%的副作用出现于给药的2个月内,血液学异常的50%以上在用药的3个月后出现。结论 抗结核药物引起的副作用常见,分布较广,应引起临床工作者高度重视。

Abstract: Objective To illustrate the side effects of antituberculous agents.Methods The clinincal data of pulmonary tuberculosis patients during 1990~1998 were analyzed.Results Various side effects resulting from antituberculous agents were confirmed in 604 cases (32.7%),liver injury,acoustic nerve injury,blood system injury,gastrointestinal response of them were primary (82.1%).Stopped treatment rate was 14.6%.77% in side effects occurred within 2 months after administration,but the blood system injury occurred after 3 months.Conclusion The side effects of antituberculous agents were common and extensive in distribution,clinical doctors must think highly of the matter.