Research progress on interstitial lung disease combined with Mycobacterium tuberculosis infection

doi:10.19982/j.issn.1000-6621.20240171

Abstract

Abstract:

Interstitial lung disease (ILD) and pulmonary tuberculosis (TB) are two prevalent respiratory diseases that can significantly impact health. TB, caused by Mycobacterium tuberculosis, is an infectious disease imposing a severe disease burden globally. In contrast, ILD is a group of non-communicable lung diseases characterized by chronic inflammation and alveolar interstitial fibrosis, profoundly affecting patients’ quality of life and prognosis. The interstitial and fibrotic changes in the lungs can mask signs of infection, while Mycobacterium tuberculosis infection can further worsen the condition of ILD. Therefore, when TB and ILD coexist, their interaction complicates timely diagnosis and treatment, adversely affecting the disease prognosis and outcome. This review summarizes the research progress in the epidemiology, pathogenesis, diagnostic methods, high-risk factors, and treatment of ILD combined with Mycobacterium tuberculosis infection, aiming to provide references for clinical diagnosis and treatment.

Key words: Interstitial lung disease, Mycobacterium tuberculosis, Infection, Comorbidity, Consensus development conferences as topic

CLC Number:

R563
R52

Fu Keyan, Zhu Bangzheng, Ye Jian. Research progress on interstitial lung disease combined with Mycobacterium tuberculosis infection[J]. Chinese Journal of Antituberculosis, 2024, 46(7): 823-829. doi: 10.19982/j.issn.1000-6621.20240171

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