Research progress on diagnosis methods of tuberculous meningitis

doi:10.3969/j.issn.1000-6621.2021.07.016

Abstract

Abstract:

Tuberculous meningitis (TBM) is the most common tuberculosis of the central nervous system and the most severe extra-pulmonary tuberculosis, which often onset with nonspecific symptoms. At present, all TBM diagnostic techniques are not perfect. Although the cerebrospinal fluid (CSF) of patients changes obviously, it is still not specific. In addition, the bacterial load in CSF is very low, the diagnostic sensitivity of relevant laboratory testing techniques is low, and the duration is long. This artical summarized problems of the diagnosis of TBM, reviewed the recent research progress and advantages or disadvantages of different diagnostic methods for TBM,in order to improve the diagnosis rate of TBM and avoid delay of treatment.

Key words: Tuberculosis, pleural, Etiological diagnosis, Diagnostic imaging, Review literature as topic

WANG Le-le, GUO Jian-qiong, YANG Song, TANG Shen-jie. Research progress on diagnosis methods of tuberculous meningitis[J]. Chinese Journal of Antituberculosis, 2021, 43(7): 735-740. doi: 10.3969/j.issn.1000-6621.2021.07.016

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