Abstract:

Objective: To analyze treatment outcomes and influencing factors of patients with pulmonary tuberculosis complicated with diabetes mellitus (PTB-DM) in Jilin Province from 2018 to 2022, and to provide a basis for improving PTB-DM prevention and control strategy. Methods: Data of PTB patients in Jilin Province from 2018 to 2022 were collected through the Tuberculosis Management Information System of the China Disease Control and Prevention Information System. Characteristics and treatment outcomes of PTB-DM patients were analyzed using descriptive methods. Binary logistic regression model was used to analyze influencing factors of treatment outcomes. Results: From 2018 to 2022, a total of 2640 PTB-DM patients were registered in Jilin Province, accounting for 5.67% (2640/46594) of the total population of PTB patients, which increased from 3.45% (468/13569) in 2018 to 9.10% (573/6296) in 2022, showing a yearly increasing trend ($χ^{2}_{trend}$=302.583, P<0.05). PTB-DM patients were mainly male (79.02%, 2086/2640), 45 to 64 years old (61.36%, 1620/2640), etiologically positive (77.61%, 2049/2640). The treatment success rate of PTB-DM patients in the province was 89.37% (2119/2371), and the adverse outcome incidence was 10.63% (252/2371).Multivariable logistic regression analysis showed that age group of ≥65 years (OR=1.573, 95%CI:1.009-2.452), etiologically positive (OR=1.471, 95%CI:1.029-2.104), receiving retreatment(OR=2.311, 95%CI:1.565-3.412), floating population(OR=4.745, 95%CI: 3.359-6.704) were risk factors for adverse outcomes in PTB-DM patients. Conclusion: The treatment outcomes of PTB-DM patients in Jilin Province are generally poor, so more attention should be paid to PTB-DM patients over 65 years old, etiologically positive, receiving retreatment, and floating population.

Key words: Tuberculosis, pulmonary, Diabetes mellitus, Treatment outcome, Factor analysis, statistical