Value of protected bronchoalveolar lavage (PBAL) in diagnosing sputum-negative pulmonary tuberculosis

Abstract

Abstract: Objective To explorethe value of Protected Bronchoalveolar Lavage (PBAL) in diagnosing sputum-negative pulmonary tuberculosis. Method 96 sputum-negative pulmonary tuberculosis patients were investigated. All patients underwent flexible bronchoscopy examination by protected bronchoalveolar lavage (PBAL). The specimen of the PBAL was detected by acid-fast bacilli (AFB), Lowenstein-Jensen culture and BACTEC rapid culture technique. Results The positive rate of PBAL specimen acid-fast bacilli positive was 20.8% (20/96), of Lowenstein-Jensen culture was 31.3% (30/96), of BACTEC MGIT 960 culture was 61.5% (59/96). Finally, 62(64.6%)patients were diagnosed. Conclusion PBAL has an important role in the diagnosis of sputum-negative pulmonary tuberculosis, and multi-techniques may improve the diagnostic value.

Key words: pulmonary tuberculosis, Protected Bronchoalveolar Lavage, culture

Li Xingbin¹,Zhang Guangyu,Du Xiuran, et al.. Value of protected bronchoalveolar lavage (PBAL) in diagnosing sputum-negative pulmonary tuberculosis[J]. Chinese Journal of Antituberculosis, 2008, 30(5): 421-423.

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