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Chinese Journal of Antituberculosis ›› 2003, Vol. 25 ›› Issue (6): 379-381.

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Evaluation of the application for fast cultivation an d drug susceptibility tests by BACTEC-MGIT960 in diagnosis and treatment of patients with pulmonary tuberculosis

WANG Wei,LI Hong-ming,WANG An-sheng,et al.   

  1. Department of Tuberculosis,The 309th Hospital of PLA,Beijing 100091
  • Online:2003-06-10 Published:2003-11-03

Abstract: Objective To evaluate the application for fast cultivation and susceptibility tests by BACTEC-MGIT960 in diagnosis and treatment of patients with pulmonary tuberculosis.Methods Fast cultivation of mycobactria tuberculous and suscept ibility tests by BACTEC-MGIT960 and compared with improved 7H9 drug medium and improved L-J medium.Results Average report time of cultivation and drug susceptibil ity tests by BACTEC-MGIT960 was only 8.5 d and 6.5 d,it was shorter than that o f improved 7H9 medium (20.6 d and 17 d) and improved L-J medium.(30.8 d and 26. 5 d).Indentical proportion of drug susceptibility tests was higher than 90%.Conclusion The fast cultivation and drug susceptibility tests b y BACTEC-MGIT960 is helpful to diagnosis and treatment of patients with pulmona ry tuberculosis,and it is a quick,efficient and relieble method.

Key words: Mycobacterium tuberculosis, BACTEC-MGIT960, Tuber culosis,pulmonary