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中国防痨杂志 ›› 2002, Vol. 24 ›› Issue (5): 252-253.

• 论著 • 上一篇    下一篇

支气管肺泡灌洗液心钠素测定对良恶性肺部疾病鉴别诊断的研究

王子玲;张纪洲;盛喜玲;王怡冰;张伟;张霞;王宁;   

  1. 河南省胸科医院 郑州 450003;
  • 出版日期:2002-05-10 发布日期:2002-11-03

Study of discriminating benign and malignance from lung disease by atrial natriuretic polypeptide in bronchia alveolus lavage fluid

WANG Zi ling, ZHANG Ji zhou, SHENG Xi ling, et al.   

  1. Henan Provincial Chest Hospital, Zhengzhou, 450003
  • Online:2002-05-10 Published:2002-11-03

摘要: 目的 研究支气管肺泡灌洗液心钠素(ANP)对良性和恶性肺部疾病的鉴别诊断价值。方法 采用放射免疫测定法测定了60例肺良性疾病患者(其中结核30例,炎症30例)和34例肺癌患者支气管肺泡灌洗液心钠素含量。结果 肺癌支气管肺泡灌洗液(BALF)中的ANP水平显著高于肺良性疾病组(P<0.01),有显著性差异。结论 测定BALF中ANP水平是良恶性肺部疾病鉴别诊断的一项有价值的指标。

关键词: 支气管肺泡灌洗液, 心钠素, 肺部疾病

Abstract: Objective To study the discrimination diagnosis value of atrial natriuretic peptide (ANP) on benign and malignance lung disease. Methods The levels of ANP in (BALF) were determined by radioimmunoassay (RIA), from 34 cases of lung cancer and 60 cases of benign lung disease. Results The levels of ANP in BALF from patients with lung cancer are significantly higher than those in benign lung disease (P<0.01). Conclusions ANP adopted simultaneously can increase the diagnosis level in differentiating malignance from benign lung disease.

Key words: Bronchia alveolus lavage fluid, Atrial natriuretic peptide, Lung disease