Advances in reseach on Mycobacterium tuberculosis drug resistance mechanism

Abstract

Abstract: Tuberculosis was one of most serious infectious diseases that were harmful to human health. Antibiotics was effective treatment against this bacterium. But the emergency of multi- and extensively drug-resistant Mycobacterium tuberculosis(Mtb) were occurred frequently when the use of antibiotics was unproper. Drugresistant phenotype was due to mutations in drug resistant related genes, this paper will state the progress in mechanism study of drug resistant Mtb, which will guide the diagnosis and treatment of drug resistant Mtb.

Key words: Antitubercular agents, Antibiotics, antitubercular, Drug resistance, bacterial

DING Hai-rong, QIN Chuan, ZHAN Ling-jun. Advances in reseach on Mycobacterium tuberculosis drug resistance mechanism[J]. Chinese Journal of Antituberculosis, 2013, 35(8): 615-620.

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