Effects of anti-tubercular agents on intestinal flora and its influence on the organism

doi:10.3969/j.issn.1000-6621.2020.12.016

Abstract

Abstract:

The structure and metabolites of intestinal flora interact with the human body, to maintain the steady state of intestinal barrier, promote the balance of nutrition metabolism and immunity, and take participate in the pathological and physiological processes of various systems, tissues and organs. It has significant effect on the process of TB infection, pathogenesis, treatment and prognosis. However, the study of the effect of anti-tubercular agents on intestinal flora is limited. The authors reviewed the effect of intestinal flora on steady state of intestinal barrier, summarized the research results of the effect of anti-tubercular agents on intestinal flora, expanded related clinical issues, and discussed the extensive effect of intestinal flora changes on the organism.

Key words: Tuberculosis, Antitubercular agents, Bacteria, Enterobacteriaceae, Causality, Review literature as topic

TANG Liang, BAO Yu-cheng, ZHANG Wen-long. Effects of anti-tubercular agents on intestinal flora and its influence on the organism[J]. Chinese Journal of Antituberculosis, 2020, 42(12): 1333-1338. doi: 10.3969/j.issn.1000-6621.2020.12.016

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