Abstract: Objective To explore the impacts on treatment effect with medication management system for pulmonary tuberculosis. Methods Three hundred cases with pulmonary tuberculosis notified in Yuexiu district from January to June 2011,were selected and randomly divided into study group and control group,with 150 cases in each group. The study group was managed with medication management system and the control group was managed with routine treatment supervision. The regular treatment rate and cure rate were evaluated at the end of treatment. Results The regular treatment rate of the study group was 99.3%（149/150）,while that of the control group was 84.0%（126/150）,and there was significant difference（χ²=23.084, P<0.05）. The cure rate of the study group（97.3%（146/150））was significantly higher than the control group（83.3%（125/150））（χ²=16.834, P<0.05）. Conclusion The medication management system can improve the regular treatment rate and the cure rate of pulmonary tuberculosis cases.

Key words: Tuberculosis, pulmonary/drug therapy, Medication therapy management, Medication adherence, Treatment outcome