Abstract:

A total of 5 patients with spinal tuberculosis (TB) and HIV co-infection (observation group) and 5 patients with spinal TB only (control group), who received surgical treatment in the Guiyang City Public Health Treatment Center of Guizhou Province from 2013 to 2018 and met the admission criteria, were enrolled into this study. The sex, age and operation methods of the patients in the observation group and control group were matched. The author compared the clinical data of the patients in both groups and to explore the surgical treatment strategy of the patients with spinal TB and HIV co-infection. It was found that, when the CD4 ⁺ T-lymphocyte count of the patients in the observation group was evaluated and corrected before the operation and the standardized disinfection and isolation procedures and the three-level occupational exposure protection principles (all surgical medical staff wore masks with protective glasses, double-layer latex gloves, disposable waterproof surgical clothes, sleeves and boots) were strictly adhered during the operation, there was no significant difference between the two groups in the selection of surgical methods, age, intraoperative hemorrhage, postoperative drainage, and VAS score (Ps>0.05). However, the average operation time in the observation group ((3.0±0. 9) h) was significant higher than that in the control group ((2.7±0. 6) h) (t=-0. 424, P=0. 004). One patient in the observation group appeared the drainage sinus in one week after discharged from the hospital and it gradually healed in 3 months of debridement, dressing change and control of CD4 ⁺ T-lymphocyte count.

Key words: Tuberculosis, spinal, HIV infections, Comorbidity, Surgical procedures, operative, Treatment outcome, Comparative study