Chinese Journal of Antituberculosis ›› 2011, Vol. 33 ›› Issue (9): 566-569.
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XU Yu
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Abstract: Objective To understand clinical use of anti-tuberculosis drugs in Beijing Haidian Hospital and provide evidence for rationale use of anti-tuberculosis drugs in general hospitals. Methods Medication rationality was evaluated by DDDs, DDC and DUI calculated based on total use, money and days using drugs of first-line anti-tuberculosis drugs in 2010 using computer information system. Sixty-two patients were detected from 17321 in-hospital patients, and their reasons for medication, regimen, and dosage were analyzed. Results The first-line drugs which can be used in Beijing Haidian Hospital were rifampicin(RFP), isoniazid(INH), ethambutol(EMB),pyrazinamide(PZA), and streptomycin(SM) The whole year’s expense on all first-line anti-tuberculosis drugs was 1988.05 RMB. The DUI value of RFP, EMB and PZA were 0.85, 0.86 and 0.96, respectively. Forty-eight patients were treated with anti-tuberculosis drugs as treatment aim among 62 patients who received the first-line anti-tuberculosis drugs. Among 32 confirmed and clinical diagnosed patients, only 43.8%(14/32)received HRZE regimen. Addition of levofloxacin(Lfx) to the regimen in patients who received second-line anti-tuberculosis drug accounted for 79.2%(38/48).Conclusion The dosage of antituberculosis drugs was less in Haidian hospital. The rate of standardized clinical use of antituberculosis drugs is low and some agent dosage isn’t enough. Standard treatment of tuberculosis should be strengthened in the future.
Key words: Antitubercular agents, Drug utilization, Beijing city
XU Yu. Clinical use of antituberculosis drugs in Beijing Haidian Hospital in 2010[J]. Chinese Journal of Antituberculosis, 2011, 33(9): 566-569.
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