Abstract: Objective To understand the impact of non-therapeutic factors on TB treatment outcome of patients co-infected with TB/HIV disease.  Methods All newly discovered TB/HIV patients during 2007—2008 from 6 counties were observed, non-therapeutic factors including sex, age, occupation, education level, and marital status were analyzed.  Result Taking treatment success (cure and treatment completion), loss (treatment interruption) as outcome variables, 294 patients were included enrolled in this study. The majority of patients were middle-aged or youth male. HIV was mainly transmitted through intravenous drug use and sex. Nearly one third of patients had no regular employment, and their education level was primary school or even less, marital status was divorced or widowed. Patients with lower education level, divorced or widowed are more likely to interrupt the treatment.  Conclusion In order to reduce the interruption rate of TB treatment, we should pay more attention to patient’s psychological support and health education before and after treatment, especially for patients with non-regular employment, lower education level, divorced or widowed.

Key words: AIDS, tuberculosis/therapy, superinfection, treatment outcome