Abstract: Objective To evaluate the efficacy and safety of feitai capsule,a kind of Chinese traditional medicine, as adjuvant treatment for new patients with smear positive pulmonary tuberculosis. Methods 120 new cases with smear positive pulmonary tuberculosis which were prospectively enrolled from June 2006-June 2007 were assigned into either to receive standard anti-TB regimen with feitai capsule(treatment arm) or to receive standard anti-TB regimen only (control arm). Index of efficacy for symptoms, rates of sputum conversion, X-rays focus absorption and cavity closed at the end of the second month and the sixth month during the course of treatment were recorded.  Results 57 cases in treatment group and 55 cases in the control completed the treatment. The therapeutic index, rates of sputum conversion, X-rays focus absorption and cavity closed in the treatment group were higher than those of control group after six months during the course of treatment(P<0.05). The rate of side effects on feitai capsule was only 5.26%(3/57). Conclusion s Fetai capsule can effectively alleviate the symptoms of TB patients, also improve the rate of focus absorption, cavity closed and sputum conversion, and long-term using is safe.

Key words: tuberculosis,pulmonary/traditional Chinese drug theropy, autitubercular agents(TCD), treatment outcome