Abstract:

The patients with tuberculous peritonitis who were hospitalized in Tuberculosis Hospital of Shaanxi Province from January 2013 to January 2015 were collected in this study. According to the different medication regimens, 42 cases were randomly selected by random digital table method as control group from 86 cases who were treated with simple Western medicine (drug regimen: 3H-R-Z-E/15H-R-E), and 42 cases were randomly selected as observational group from 94 cases who were treated with traditional Chinese medicine in combination with Western medicine (drug regimen: 3H-R-Z-E/15H-R-E combined with Tingli Dazao Xiefei Soup, in which the soup was took for 3 months). The efficacy, liver injury and recurrence rate after treatment of the two groups were statistically analyzed. After 3 months of treatment, the total effective rate of the observational group was 92.9% (39/42), significantly higher than that of the control group (76.2% (32/42); the difference was statistically signi-ficant (Z=1.93, P=0.013). The incidence of liver injury in the observational group (4.8%, 2/42) was lower than that in the control group (28.6%, 12/42), and the difference was statistically significant (χ ²=8.57, P=0.002). All 84 patients completed the course of treatment and were followed up for one year after the end of treatment. The rate of recurrence in the observational group (6.7%, 2/30) was lower than that in the control group (32.0%, 8/25), and the difference was statistically significant (χ ²=6.12, P=0.013). The combination of Chinese and western medicine in the treatment of tuberculous peritonitis has the advantages of high cure, low recurrence rate and small liver injury.

Key words: Peritonitis, tuberculous, Drugs, Chinese herbal, Treatment outcome, Comparative effectiveness research