Chinese Journal of Antituberculosis ›› 2023, Vol. 45 ›› Issue (3): 297-304.doi: 10.19982/j.issn.1000-6621.20220370
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Cai Yuguo, Zheng Yongli, He Min, Pu Yu()
Received:
2022-09-28
Online:
2023-03-10
Published:
2023-03-07
Contact:
Pu Yu
E-mail:599080188@qq.com
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CLC Number:
Cai Yuguo, Zheng Yongli, He Min, Pu Yu. Construction and validation of early diagnosis model of knee joint tuberculosis based on LASSO regression[J]. Chinese Journal of Antituberculosis, 2023, 45(3): 297-304. doi: 10.19982/j.issn.1000-6621.20220370
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URL: http://www.zgflzz.cn/EN/10.19982/j.issn.1000-6621.20220370
因素 | 病例组(136例) | 对照组(136例) | 统计检验值 | P值 |
---|---|---|---|---|
性别 | χ2=5.323 | 0.021 | ||
男性 | 81(59.56) | 62(45.59) | ||
女性 | 55(40.44) | 74(54.41) | ||
年龄(岁, | 45.42±17.86 | 50.74±18.50 | t=2.415 | 0.016 |
BMI指数( | 22.19±2.65 | 22.39±2.72 | t=-0.595 | 0.553 |
IFN-γ释放水平(pg/ml, | 236.67±90.73 | 137.25±32.04 | t=12.050 | <0.001 |
LAM抗体 | χ2=82.693 | <0.001 | ||
阴性 | 42(30.88) | 116(85.29) | ||
阳性 | 94(69.12) | 20(14.71) | ||
GeneXpert MTB/RIF | χ2=74.395 | <0.001 | ||
阴性 | 50(36.76) | 119(87.50) | ||
阳性 | 86(63.24) | 17(12.50) | ||
骨髓水肿 | χ2=19.009 | <0.001 | ||
无 | 83(61.03) | 115(84.56) | ||
有 | 53(38.97) | 21(15.44) | ||
半月板损伤 | χ2=6.380 | 0.012 | ||
无 | 77(56.62) | 97(71.32) | ||
有 | 59(43.38) | 39(28.68) | ||
软骨损伤 | χ2=24.817 | <0.001 | ||
无 | 75(55.15) | 113(83.09) | ||
有 | 61(44.85) | 23(16.91) | ||
周围组织肿胀 | χ2=3.958 | 0.047 | ||
无 | 126(92.65) | 133(97.79) | ||
有 | 10(7.35) | 3(2.21) | ||
骨质破坏 | χ2=6.942 | 0.008 | ||
无 | 127(93.38) | 113(83.09) | ||
有 | 9(6.62) | 23(16.91) | ||
关节间隙狭窄 | χ2=8.957 | 0.003 | ||
无 | 117(86.03) | 131(96.32) | ||
有 | 19(13.97) | 5(3.68) | ||
关节周围脓肿形成 | χ2=9.967 | 0.002 | ||
无 | 111(81.62) | 128(94.12) | ||
有 | 25(18.38) | 8(5.88) | ||
膝关节肿胀 | χ2=0.530 | 0.467 | ||
无 | 64(47.06) | 70(51.47) | ||
有 | 72(52.94) | 66(48.53) | ||
疼痛 | χ2=0.565 | 0.452 | ||
无 | 48(35.29) | 54(39.71) | ||
有 | 88(64.71) | 82(60.29) | ||
局部肌肉萎缩 | χ2=5.723 | 0.017 | ||
无 | 94(69.12) | 111(81.62) | ||
有 | 42(30.88) | 25(18.38) |
因素 | β值 | s | Wald χ2值 | P值 | OR值 | 95%置信区间 | |
---|---|---|---|---|---|---|---|
下限 | 上限 | ||||||
性别 | -0.383 | 0.406 | 0.889 | 0.346 | 0.682 | 0.308 | 1.511 |
年龄 | -0.023 | 0.011 | 4.350 | 0.037 | 0.977 | 0.955 | 0.999 |
IFN-γ释放水平 | 0.005 | 0.002 | 6.250 | 0.012 | 1.005 | 1.001 | 1.009 |
LAM抗体 | 2.731 | 0.451 | 36.706 | <0.001 | 15.348 | 6.344 | 37.130 |
GeneXpert MTB/RIF | 3.048 | 0.477 | 40.905 | <0.001 | 21.073 | 8.281 | 53.628 |
骨髓水肿 | 1.097 | 0.482 | 5.186 | 0.023 | 2.996 | 1.165 | 7.702 |
半月板损伤 | 1.611 | 0.503 | 10.249 | 0.001 | 5.007 | 1.868 | 13.425 |
软骨损伤 | 1.415 | 0.467 | 9.195 | 0.002 | 4.117 | 1.649 | 10.274 |
周围组织肿胀 | 1.684 | 0.491 | 11.775 | 0.001 | 5.389 | 2.059 | 14.102 |
骨质破坏 | 1.090 | 0.698 | 2.436 | 0.119 | 2.973 | 0.757 | 11.682 |
关节周围脓肿形成 | 2.024 | 0.712 | 8.089 | 0.004 | 7.570 | 1.876 | 30.546 |
常量 | -3.486 | 0.927 | 14.156 | <0.001 | 0.031 |
因素 | 例数 | 构成比(%) |
---|---|---|
性别 | ||
男性 | 41 | 56.94 |
女性 | 31 | 43.06 |
LAM抗体 | ||
阴性 | 48 | 66.67 |
阳性 | 24 | 33.33 |
GeneXpert MTB/RIF | ||
阴性 | 45 | 62.50 |
阳性 | 27 | 37.50 |
骨髓水肿 | ||
无 | 43 | 59.72 |
有 | 29 | 40.28 |
半月板损伤 | ||
无 | 37 | 51.39 |
有 | 35 | 48.61 |
软骨损伤 | ||
无 | 39 | 54.17 |
有 | 33 | 45.83 |
周围组织肿胀 | ||
无 | 56 | 77.78 |
有 | 16 | 22.22 |
骨质破坏 | ||
无 | 59 | 81.94 |
有 | 13 | 18.06 |
关节间隙狭窄 | ||
无 | 48 | 66.67 |
有 | 24 | 33.33 |
关节周围脓肿形成 | ||
无 | 46 | 63.89 |
有 | 26 | 36.11 |
膝关节肿胀 | ||
无 | 37 | 51.39 |
有 | 35 | 48.61 |
疼痛 | ||
无 | 32 | 44.44 |
有 | 40 | 55.56 |
局部肌肉萎缩 | ||
无 | 36 | 50.00 |
有 | 36 | 50.00 |
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