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中国防痨杂志 ›› 2013, Vol. 35 ›› Issue (10): 799-802.

• 论著 • 上一篇    下一篇

广东省全球基金耐多药结核病项目阶段性实施情况分析

吴惠忠 尹建军 钟耐容 蒋莉 李建伟 周琳 钟球   

  1. 510630  广州,广东省结核病控制中心
  • 收稿日期:2013-06-06 出版日期:2013-10-10 发布日期:2014-01-03
  • 通信作者: 钟球;周琳 E-mail:zhongqiu@vip.163.com; gdtb@vip.163.com
  • 基金资助:

    中国全球基金结核病项目(CHN-S10-G14-T);“十二五”国家重大科技专项(2012ZX10004903)

Effect analysis of global fund multi-drug resistant tuberculosis project in Guangdong province

WU Hui-zhong, YIN Jian-jun, ZHONG Nai-rong, JIANG Li, LI Jian-wei, ZHOU Lin, ZHONG Qiu   

  1. Centre for Tuberculosis Control of Guangdong Province, Guangzhou 510630, China
  • Received:2013-06-06 Online:2013-10-10 Published:2014-01-03
  • Contact: ZHONG Qiu; ZHOU Lin E-mail:zhongqiu@vip.163.com; gdtb@vip.163.com

摘要: 目的  分析广东省全球基金耐多药结核病项目(简称“项目”)实施效果,为广东省下一步耐多药结核病控制工作提供借鉴。 方法  搜集2006年10月至2012年12月“项目”执行期间6个地(市)上报的项目季报表、月报表,进行回顾性分析。 结果  截至2012年12月底,共筛查耐多药可疑者12 165例,进行痰培养的可疑者为12 125例,进行药敏试验的可疑者为8633例。确诊MDR-TB共1170例,纳入全球基金结核病项目治疗488例, 共有221例耐多药肺结核患者纳入治疗满2年,其中治愈99例,完成治疗5例,治疗成功率为47.06% (104/221)。 结论  通过“项目”的阶段性实施, 初步建立了耐多药结核病诊断治疗管理模式并探索了以标准方案为主的治疗策略,取得一定的成效。

关键词: 结核,肺/预防和控制, 抗药性, 多种, 细菌, 卫生计划实施, 广东省

Abstract: Objective To analyze and evaluate the implementation effect of global fund multi-drug resistant tuberculosis (MDR-TB) project, in order to provide reference for MDR-TB control work in Guangdong province. Methods Monthly and quarterly reports are all collected for retrospective analysis from Oct.2006 to Dec.2010. Results By the end of Nov.2012, a total of 12 165 MDR-TB suspects were screened, among which 12 125 cases received sputum culture, 8633 suspect cases performed drug susceptibility test (DST). 1170 MDR-TB patients were confirmed and 488 cases were recruited for treatment. A total of 221 MDR-TB cases included in treatment for 2 years, 99 cases were cured, and 5 cases completed treatment. The treatment success rate was 47.06%(104/221). Conclusion With the implementation of the MDR-TB project, we established the MDR-TB diagnosis, treatment and management model. The standard treatment regimen as the main strategy is feasible.

Key words: Tuberculosis, pulmonary/prevention &, control, Drug resistance, multiple, bacterial, Health plan implementation, Guangdong province