上海市1987年～1996年分支杆菌菌种鉴定结果分析

中国防痨杂志 ›› 1999, Vol. 21 ›› Issue (1): 34-36.

上海市1987年～1996年分支杆菌菌种鉴定结果分析

胡忠义；蔡慧梅；李来娣；屠梅欣；

上海市结核病防治中心；

收稿日期:1998-07-14 修回日期:1998-10-20 出版日期:1999-01-10 发布日期:1999-01-10

Analysis of the identification of Mycobacterium species in strians during the period 1987～1996 in Shanghai

Hu Zhongyi,Cai Huimei,Li Laidi,et al.

Hu Zhongyi,Cai Huimei,Li Laidi,et al.Shanghai Tuberculosis control Centre 200031

Received:1998-07-14 Revised:1998-10-20 Online:1999-01-10 Published:1999-01-10

摘要/Abstract

摘要： 目的对上海市1987年~1996年鉴定的5619株分支杆菌菌种鉴定结果进行分析,对其中非结核分支杆菌耐药性测定结果进行探讨?方法全部菌株的鉴定按1984年全国结核病细菌学检验规程进行?结果人型5465株(97.3%)?牛型22株(0.4%)?非结核分支杆菌132株(2.3%),其中偶发42株?胞内30株?龟型17株?瘰疬10株?堪萨斯9株?戈登9株?浅黄6株?草分支4株?不产色2株?金色2株?溃疡1株?非结核分支杆菌(MOTT)对PAS?INH?SM?RFP?EMB与KM的耐药率分别为72.4%?61.2%?49.0%?43.9%?31.6%和27.6%?对1~6种药物的耐药率分别为13.3%?21.4%?24.5%?16.3%?10.2%和6.1%?结论上海市肺结核患者感染菌种主要为人型结核分支杆菌(97.3%),而牛型(0.4%)和非结核分支杆菌(MOTT,2.3%)所占比重很小,明显低于全国水平?MOTT耐药率高应引起重视。

关键词: 分支杆菌, 菌种鉴定

Abstract: Objective To analysis of the identification of Mycobacterium species in strains and drug resistance of Mycobacterium other than Tuberculosis(MOTT) during The periol 1987～1996 in Shanghai.Methods The specific identification of Mycobacteriam and drug susceptibility test were conducted with traditional methods.Results The strains of M.tuberculosis,M.bovis and M.nontuberculosis were 5465(97.3%),22(0.4%),and 132(2.3%)respectively.There were 42 strains of M.tortuitum,30 of M.intrcellulare,17 of M.chelonae subsp,10 of M.scrofulaceum,9 of M.kansnsii,9 of M.gordonae,6 of M.gilvum,4 of M.phlei,2 of M.nonchromogenicum,2 of M.aurum and 1 of M.ulcerans respectively in total of 132 M.nontuberculosis.The rate of resistance to PAS was 72.4%,to INH 61.2%,to SM 49.0%,to RFP 43.9%,to EMB 31.6% and to KM 27.6%.The rate of resistance to only one agent was 13.3%,to two 21.4%,to three 24.5%,to four 16.3%,to five 10.2% and to six 6.1% respectively.Conclusion The pulmonary tuberculosis cases in Shanghai were infected mainly with M.tuberculosis(97.3%)and infected by MOTT only 2.3%,but the high resistance rate of MOTT should be pay great attention.

Key words: Mycobacterium, Specific identification

胡忠义, 蔡慧梅, 李来娣, 屠梅欣, . 上海市1987年～1996年分支杆菌菌种鉴定结果分析[J]. 中国防痨杂志, 1999, 21(1): 34-36.

Hu Zhongyi,Cai Huimei,Li Laidi,et al.. Analysis of the identification of Mycobacterium species in strians during the period 1987～1996 in Shanghai[J]. Chinese Journal of Antituberculosis, 1999, 21(1): 34-36.

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