结核分枝杆菌感染中一些重要免疫细胞和细胞因子作用的研究进展

摘要/Abstract

摘要： 结核病是由结核分枝杆菌（Mycobacterium tuber-culosis M.TB）感染引起的，目前世界上死亡率最高的慢性传染病。每年约有800万人发病，200万人死亡^[1]。结核分枝杆菌寄生在巨噬细胞内，主要引起细胞介导的免疫反应。有效的疫苗和快速的诊断是控制此病的关键。本文综述了人体对抗结核分枝杆菌感染自然免疫中一些重要成分如巨噬细胞、中性粒细胞和自然杀伤细胞等的作用，也讨论了CD4和CD8 T细胞的重要作用。除此以外一些重要细胞因子如IFN-γ，TNF-α和IL-12等作用的研究进展也在此阐述。

柏雪莲,傅斌,刘克义. 结核分枝杆菌感染中一些重要免疫细胞和细胞因子作用的研究进展[J]. 中国防痨杂志, 2006, 28(3): 178-182.

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