初治涂阳肺结核不固定化疗期短程化疗远期疗效观察

中国防痨杂志 ›› 2002, Vol. 24 ›› Issue (4): 216-218.

初治涂阳肺结核不固定化疗期短程化疗远期疗效观察

陈忠熙；乔炳海；陶洪文；付涛；黄巧云；金金法；

浙江省义乌市防疫站义乌 322000；

出版日期:2002-04-10 发布日期:2002-11-03

Study on forward curative effect of unfixed continuation phase short-course chemotherapy for smear positive untreated pulmonary tuberculosis

CHEN Zhong xi,QIAO Bing hai,TAO Hong wen,et al.

Yiwu Health and Prevention Station,Yiwu 322000

Online:2002-04-10 Published:2002-11-03

摘要/Abstract

摘要： 目的　在6个月固定化疗期全程每日给药化疗方案的基础上,观察进一步缩短化疗期的远期疗效。方法采用2HRZS(E)/XH₃R₃化疗方案治疗初治涂阳肺结核,经涂片检查痰菌阴转后连续3个月阴性为治疗停药标准,并注意抓好研究过程中的环节质量控制。结果符合选例标准95例,92例完成规则治疗,累计痰菌阴转率为98.9%,91例治愈,平均化疗期为5.1个月,2年随访率为91.2%,细菌学复发率为2.3%。结论本研究与国内6个月标准短化相比,其复发率相近。说明本方案治愈率高,可缩短治疗期。

关键词: 结核,肺/药物疗法, 治疗转归

Abstract: Objective To investigate the forward curative effect of further shortening the chemotherapy on the basis of 6 months chemotherapy regimen.Methods The 2HRZS(E)/ XH ₃R ₃ regimen was used in smear positive untreated pulmonary tuberculosis patients.The treatment was continued till sputum negative conversion maintained for three consecutive months. The quality control was emphasized on each research stage.Result 92 cases in the study group of 95 patients completed their chemotherapy.The sputum negative conversion rate at the end of treatment was 98.9%. 91 cases were 5.1 months on the average.The bacteriological relapse rate in two year follow up was 2.3%.Conclusion The Results indicated similar Results of the bacteriological relapse rate with the short course chemotherapy in our country,which showed a high cure rate.

Key words: Tuberculosis,pulmonary/drug therapy, Treatment outcome

陈忠熙,乔炳海,陶洪文,付涛,黄巧云,金金法,. 初治涂阳肺结核不固定化疗期短程化疗远期疗效观察[J]. 中国防痨杂志, 2002, 24(4): 216-218.

CHEN Zhong xi,QIAO Bing hai,TAO Hong wen,et al.. Study on forward curative effect of unfixed continuation phase short-course chemotherapy for smear positive untreated pulmonary tuberculosis[J]. Chinese Journal of Antituberculosis, 2002, 24(4): 216-218.

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