BACTEC-MGIT960快速培养药敏对肺结核诊治的应用和评价

中国防痨杂志 ›› 2003, Vol. 25 ›› Issue (6): 379-381.

BACTEC-MGIT960快速培养药敏对肺结核诊治的应用和评价

王巍；李洪敏；王安生；吴雪琼；王仲元；刘金伟；陈红兵；林明贵；王金河；李静；仲斌；丹子军；张韬；李素梅；

解放军第309医院北京 100091；

出版日期:2003-06-10 发布日期:2003-11-03

Evaluation of the application for fast cultivation an d drug susceptibility tests by BACTEC-MGIT960 in diagnosis and treatment of patients with pulmonary tuberculosis

WANG Wei,LI Hong-ming,WANG An-sheng,et al.

Department of Tuberculosis,The 309th Hospital of PLA,Beijing 100091

Online:2003-06-10 Published:2003-11-03

摘要/Abstract

摘要： 目的　BACTEC-MGIT960快速培养药敏在肺结核诊治中的应用评价。方法采用BACTEC-MGIT960进行快速培养药敏,并与改良罗氏培养基和改良7H9培养基进行比较。结果 BACTEC-MGIT960培养报告时间仅8.5d,明显短于改良7H9培养基(20.6d)和改良罗氏培养基(30.8d)。BACTEC-MGIT960药物敏感试验结果与其它检测方法相比,符合率在90%以上,平均报告时间仅6.5d,明显短于改良7H9培养基(17d)和改良罗氏培养基(26.5d)。结论 BACTEC-MGIT960快速培养药敏有助于肺结核的诊断和治疗,是一种快速、有效、可靠的方法。

关键词: 分支杆菌,结核, BACTEC-MGIT960, 结核,肺

Abstract: Objective To evaluate the application for fast cultivation and susceptibility tests by BACTEC-MGIT960 in diagnosis and treatment of patients with pulmonary tuberculosis.Methods Fast cultivation of mycobactria tuberculous and suscept ibility tests by BACTEC-MGIT960 and compared with improved 7H9 drug medium and improved L-J medium.Results Average report time of cultivation and drug susceptibil ity tests by BACTEC-MGIT960 was only 8.5 d and 6.5 d,it was shorter than that o f improved 7H9 medium (20.6 d and 17 d) and improved L-J medium.(30.8 d and 26. 5 d).Indentical proportion of drug susceptibility tests was higher than 90%.Conclusion The fast cultivation and drug susceptibility tests b y BACTEC-MGIT960 is helpful to diagnosis and treatment of patients with pulmona ry tuberculosis,and it is a quick,efficient and relieble method.

Key words: Mycobacterium tuberculosis, BACTEC-MGIT960, Tuber culosis,pulmonary

王巍,李洪敏,王安生,吴雪琼,王仲元,刘金伟,陈红兵,林明贵,王金河,李静,仲斌,丹子军,张韬,李素梅,. BACTEC-MGIT960快速培养药敏对肺结核诊治的应用和评价[J]. 中国防痨杂志, 2003, 25(6): 379-381.

WANG Wei,LI Hong-ming,WANG An-sheng,et al.. Evaluation of the application for fast cultivation an d drug susceptibility tests by BACTEC-MGIT960 in diagnosis and treatment of patients with pulmonary tuberculosis[J]. Chinese Journal of Antituberculosis, 2003, 25(6): 379-381.