Research progress of immune regulatory mechanism of traditional Chinese medicine on tuberculosis

doi:10.3969/j.issn.1000-6621.2020.02.016

Abstract

Abstract:

The pathogenesis and prognosis of tuberculosis are closely related to the host’s immune status and the growth or inhibition of Mycobacterium tuberculosis. The research has shown that many traditional Chinese medicine ingredients or extracts, such as baicalin, saxifragifolin D, rhubarb extract, isoliquiritigenin, and astragalus polysaccharide, can play an adjuvant anti-tuberculosis role by inducing macrophage autophagy, strengthening the immune function of tuberculosis patients, inhibiting or destroying the production of Mycobacterium tuberculosis and other different ways. In this paper, the immune regulation mechanism of different small molecular chemicals of traditional Chinese medicine on tuberculosis was reviewed, which provided theoretical basis for the treatment of tuberculosis with traditional Chinese medicine.

Key words: Drugs,Chinese herbal, Tuberculosis, Immunomodulation, Defense mechanisms, Chemotherapy,adjuvant, Review

XIA Lu,LU Shui-hua,LIU Ping. Research progress of immune regulatory mechanism of traditional Chinese medicine on tuberculosis[J]. Chinese Journal of Antituberculosis, 2020, 42(2): 168-172. doi: 10.3969/j.issn.1000-6621.2020.02.016

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