The applications and problems of mesenchymal stem cells for the treatment of tuberculosis

doi:10.3969/j.issn.1000-6621.2019.02.020

Abstract

Abstract:

Tuberculosis is one of the most serious infectious diseases in the world because of its high mortality and morbidity. Despite the robust immune response of human, Mycobacterium tuberculosis (MTB) evades host immunity and sets up a persistent infection. With the advances of medicine there have been some drugs to treat tuberculosis, but due to slow development of anti-tuberculosis drugs and the constant variation of MTB, prevention and management of tuberculosis is still a global health problem threatening thousands of lives. Recently, with the discovery and confirmation of its immunomodulatory property, the mesenchymal stem cells could give us new expectations for clinical management of tuberculosis. The authors summarize the applications and problems about mesenchymal stem cells for tuberculosis.

Key words: Tuberculosis, Mesenchymal stem cells, Immunomodulation, Therapeutic uses

Bei-bei WU,Wei HUANG,Zhi-min WANG. The applications and problems of mesenchymal stem cells for the treatment of tuberculosis[J]. Chinese Journal of Antituberculosis, 2019, 41(2): 233-235. doi: 10.3969/j.issn.1000-6621.2019.02.020

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