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Chinese Journal of Antituberculosis ›› 2011, Vol. 33 ›› Issue (12): 794-797.

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Analysis of influencing factors of death of patients with tuberculous meningitis

MAO Xiao-hui, WANG Bo, WU Xuan   

  1. Department of Four Medicine, Xi’an Tuberculosis and Thoracic Tumor Hospital, Xi’an 710061, China
  • Received:2011-04-18 Online:2011-12-10 Published:2012-02-15
  • Contact: MAO Xiao-hui E-mail:Mxh13991972590@163.com

Abstract: Objective  To evaluate the influencing factors of the prognosis of patients with tuberculous meningitis.  Methods  A retrospective study was conducted in Tuberculosis and Thoracic Tumor Hospital of Xi’an from January 2006 to December 2010, the clinical data (age of onset, duration, treatment of disease, radiographic changes, whether regular treatment, with or without coma and other relevant factors) of 84 cases patients with tuberculous meningitis (A group of 58 patients survived, B group, 26 patients died) were analyzed.   Results  The influencing factors of the prognosis of patients with tubercular meningitis were coma in treatment(RR=2.658), hydrocephalus(RR=4.338);having received informal anti-TB treatment outside(RR=3.551);liver damage(RR=2.046).The above 4 factors increased risk of death in patients with tuberculous meningitis (P<0.05).    Conclusion  Coma in treatment, liver damage occurred during the treatment, hydrocephalus, having received informal anti-TB treatment outside are the influencing factors of  the prognosis of patients with tuberculous meningitis. 

Key words: Tuberculosis,meningeal/mortality, Risk factors