Abstract: Objective To compare NovoRapid 30 with Novolin 30R in curative effect and security in treating type 2 diabetes mellitus complicated with pulmonary tuberculosis. Method The contrast observation was conducted randomly and openly for 12 weeks,60 patients of T₂DM complicated with pulmonary tuberculosis were divided into two groups.One group was treated by NovoRapid 30 and the other by Novolin 30R.All of them used in the way of hypodermic injection before breakfast and dinner,the blood sugar for 7 times a day was measured and HbA_lC and low blood sugar response and other side effects were also observed.In addition to this,sputum conversion and chest X-ray were observed. Result The level of blood sugar of using NovoRapid 30 after three meals was lower obviously than that of Novolin 30R(P<0.05),the rate of low blood sugar of NovoRapid 30 was lower than that of Novolin 30R,and the rate of serious low blood sugar of NovoRapid 30 was 55% of Novolin 30R,HbA_lC,amount of of the use of insulin and other side effects of the two groups have no statistically significant difference.The rate of sputum conversion rate of NovoRapid 30 was 90.4%,and that of Novolin 30R was 75%.There was statistically significant difference between the two groups(P<0.05).The number of the cases with absorption of chest X-ray of NovoRapid 30 was 19 and that of Novolin 30R was 18.There was no statistically significant difference between them. Conclusion The effect of NovoRapid 30 in controlling blood sugar after breakfast and dinner is more satisfied than that of Novolin 30R.The rate of low blood sugar is lower,and the rate of sputum conversion is higher.Thus,to select NovoRapid 30 to treat T₂DM complicated with pulmonary tuberculosis is better than Novolin 30R.

Key words: NovoRapid 30, Novolin 30R, T₂DM complicated, pulmonary tuberculosis