Abstract: Objective To investigate resistant situation to anti-TB drugs among inpatients with pulmonary TB in the Baoli Hospital of Ningbo and the difference of drug resistance among patients from cities,towns and rural area and patients floating to cities. Methods Analysis was conducted on drug resistant tests to INH,SM,RFP and EMB of patients with sputum culture positive pulmonary TB hospitalized in our hospital from January 1992 to December 2003. Results The total initial drug resistance rate was 21.4%,11.5%,14.1%19.4% and 28.6% respectively for patients from cities,towns,other parts floating to cites and rural area. The total acquired drug resistance rate was 77.8%,56.9%,75%,85.7% and 89% respectively for patients from cites,towns,other parts floating to cites and rural area. Conclusion Resistance to Anti-TB drugs was the highest among rural inpatients and then,the inpatients floating to cites,from towns and cites.

Key words: Tuberculosis, Initial Drug-Resistance, Acquired drug resistance.