Abstract: Objective To analysis the acid-base imbalance of serious pulmonary tuberculosis with infection.Method Samples of groin arterial blood from 120 patients were assayed with ABL-505 gas-electrolyte analysis instrument.According to the values of pH,PCO 2 and HCO - 3,acid-base imbalances were classified a simple or mix.Subsequently,based on the values of AG,we judged whether trio acid-base imbalance existed.Results The occurrence of acid-base imbalance were of simple>mix>trio and respiratory acidosis>respiratory alkalosis.Metabolic acidosis had the same occurrence with metabolic alkalosis.The effective treatment of pulmonary infection made it easy to correct the acid-base imbalance. Conclusion With infection occured,the lung tissue of patients with serious pulmonary tuberculosis were destroied more seriously.Ventilation-perfusion and V A/Q A disorders can occur,which resulted in acid-base imbalance.It is the most importance to treat the pulmonary infection and the main methods are correcting acid-base imbalance and disorder of electrolyte.

Key words: Tuberculosis, pulmonary, serious, Infection