Chinese Journal of Antituberculosis ›› 2019, Vol. 41 ›› Issue (3): 248-253.doi: 10.3969/j.issn.1000-6621.2019.03.002
• Original Articles • Previous Articles Next Articles
Jian-kun ZHU,Feng JIN(),Cheng WANG,Yun-zeng ZHANG,Gao-feng QIAO,Da-wei LIU,Bin ZHAO
Received:
2019-01-16
Online:
2019-03-10
Published:
2019-03-15
Contact:
Feng JIN
E-mail:2547875348@qq.com
Jian-kun ZHU,Feng JIN,Cheng WANG,Yun-zeng ZHANG,Gao-feng QIAO,Da-wei LIU,Bin ZHAO. Analysis of clinical characteristics between lung cancer patients complicated by obsolete pulmonary tuberculosis with ground-glass opacity and with solid nodule[J]. Chinese Journal of Antituberculosis, 2019, 41(3): 248-253. doi: 10.3969/j.issn.1000-6621.2019.03.002
Add to citation manager EndNote|Ris|BibTeX
URL: https://www.zgflzz.cn/EN/10.3969/j.issn.1000-6621.2019.03.002
项目 | GGO组(16例) | SN组(29例) | 统计检验值 | P值 |
---|---|---|---|---|
年龄(岁, | 51.0±6.1 | 59.6±8.4 | t=3.58 | <0.001 |
性别[例数(构成比,%)] | χ2=0.62 | 0.430 | ||
男 | 11(68.7) | 23(79.3) | ||
女 | 5(31.3) | 6(20.7) | ||
结核病史(年, | 19.5±2.6 | 23.3±3.1 | t=4.16 | <0.001 |
确诊时间(d, | 382.0±27.0 | 9.5±5.1 | t=77.69 | 0.000 |
肿瘤TNM分期[例数(构成比,%)] | χ2=7.56 | 0.068 | ||
Tis(原位癌) | 2(12.5) | 0(0.0) | ||
T1a(TNM,微浸润癌) | 2(12.5) | 0(0.0) | ||
T1a | 1(6.25) | 5(17.2) | ||
T1b | 6(37.5) | 16(55.2) | ||
T1c | 5(31.25) | 8(27.6) | ||
淋巴结是否有转移[例数(构成比,%)] | χ2=9.99 | 0.003 | ||
N0 | 16(100.0) | 16(55.2) | ||
N1 | 0(0.0) | 9(31.0) | ||
N2 | 0(0.0) | 4(13.8) | ||
肿瘤与结核病灶位置关系[例数(构成比,%)] | χ2=4.28 | 0.038 | ||
同叶 | 4(25.0) | 18(62.1) | ||
异叶 | 12(75.0) | 11(37.9) | ||
病理类型[例数(构成比,%)] | χ2=6.78 | 0.029 | ||
鳞癌 | 1(6.25) | 12(41.4) | ||
腺癌 | 14(87.5) | 15(51.7) | ||
其他a | 1(6.25) | 2(6.9) | ||
手术方式[例数(构成比,%)] | χ2=15.66 | 0.000 | ||
肺叶切除 | 11(68.8) | 29(100.0) | ||
肺段切除 | 1(6.2) | 0(0.0) | ||
肺楔形切除 | 2(12.5) | 0(0.0) | ||
肺叶加肺楔形切除 | 2(12.5) | 0(0.0) |
[1] |
赵铭, 陈晓峰, 刘鸿程 , 等. 肺结核合并肺癌的危险因素及预后分析. 实用医学杂志, 2010,26(11):1951-1953.
doi: 10.3969/j.issn.1006-5725.2010.11.033 URL |
[2] |
姜格宁, 谢冬 . 表现为磨玻璃样影的早期肺癌. 中华外科杂志, 2015,53(10):790-793.
doi: 10.3760/cma.j.issn.0529-5815.2015.10.020 URL |
[3] |
Im JG, Itoh H, Shim YS , et al. Pulmonary tuberculosis: CT findings—early active disease and sequential change with antituberculous therapy. Radiology, 1993,186(3):653-660.
doi: 10.1148/radiology.186.3.8430169 URL pmid: 8430169 |
[4] | 郑苇菁, 高玉堂, 汪钟贤 , 等. 肺癌与肺结核关系的病例对照研究. 中华结核和呼吸杂志, 1988,11(3):135-138. |
[5] |
Engels EA, Shen M, Chapman RS , et al. Tuberculosis and subsequent risk of lung cancer in Xuanwei, China. Int J Cancer, 2009,124(5):1183-1187.
doi: 10.1002/ijc.24042 URL pmid: 2610239 |
[6] |
沈建恩, 雷涛, 王祖恩 , 等. 肺结核病人化疗依从性相关因素研究. 中国防痨杂志, 2007,29(2):133-135.
doi: 10.3969/j.issn.1000-6621.2007.02.006 URL |
[7] |
古颖春, 宋业琳, 刘玉峰 . 肺结核合并肺癌患者的临床特征及预后影响因素. 中华医学杂志, 2014,94(36):2838-2841.
doi: 10.3760/cma.j.issn.0376-2491.2014.36.009 URL |
[8] |
Hasegawa M, Sone S, Takashima S , et al. Growth rate of small lung cancers detected on mass CT screening. Br J Radiol, 2000,73(876):1252-1259.
doi: 10.1259/bjr.73.876.11205667 URL pmid: 11205667 |
[9] | 刘大伟, 朱建坤, 金锋 , 等. 以磨玻璃样密度影为表现的早期肺癌并发肺结核患者的诊治分析. 中国防痨杂志, 2019,41(1):64-68. |
[10] |
刘建民, 关玲, 侯红革 , 等. 肺结核合并肺癌的临床特点及误诊原因分析. 肿瘤基础与临床, 2012,25(5):452-453.
doi: 10.3969/j.issn.1673-5412.2012.05.034 URL |
[11] |
Kim TJ, Goo JM, Lee KW , et al. Clinical, pathological and thin-section CT features of persistent multiple ground-glass opacity nodules: comparison with solitary ground-glass opacity nodule. Lung Cancer, 2009,64(2):171-178.
doi: 10.1016/j.lungcan.2008.08.002 URL pmid: 18799230 |
[12] |
周逸鸣, 宋楠, 朱余明 , 等. 单中心连续1817例早期肺癌诊疗经验. 中华胸心血管外科杂志, 2017,33(11):655-657.
doi: 10.3760/cma.j.issn.1001-4497.2017.11.002 URL |
[13] |
陈东红, 支修益 . 亚肺叶切除治疗早期非小细胞肺癌. 首都医科大学学报, 2014,35(6):689-693.
doi: 10.3969/j.issn.1006-7795.2014.06.002 URL |
[14] |
Tsutani Y, Miyata Y, Nakayama H , et al. Sublobar resection for lung adenocarcinoma meeting node-negative criteria on preo-perative imaging. Ann Thorac Surg, 2014,97(5):1701-1707.
doi: 10.1016/j.athoracsur.2014.02.024 URL pmid: 24679941 |
[15] |
佘科霖, 李小东, 李振轩 , 等. 陈旧性肺结核对非小细胞肺癌患者CT临床N分期的影响. 中山大学学报(医学科学版), 2012,33(5):673-677.
doi: 10.3969/j.issn.1006-1959.2014.18.521 URL |
[16] |
Heuvers ME, Aerts JG, Hegmans JP , et al. History of tuberculosis as an independent prognostic factor for lung cancer survival. Lung Cancer, 2012,76(3):452-456.
doi: 10.1016/j.lungcan.2011.12.008 URL pmid: 22226628 |
[17] |
谢博雄, 丁嘉安, 姜格宁 . 肺结核合并肺癌的诊断及影响外科治疗预后的因素分析. 中华结核和呼吸杂志, 2005,28(4):230-232.
doi: 10.3760/j:issn:1001-0939.2005.04.005 URL |
[18] |
Luo YH, Wu CH, Wu WS , et al. Association between tumor epidermal growth factor receptor mutation and pulmonary tuberculosis in patients with adenocarcinoma of the lungs. J Thorac Oncol, 2012,7(2):299-305.
doi: 10.1097/JTO.0b013e31823c588d URL pmid: 22173705 |
[19] |
张军, 郑锴, 张鹏 , 等. 肺腺癌患者中EGFR突变与肺结核的相关性研究. 中国肿瘤临床, 2013,40(24):1535-1539.
doi: 10.3969/j.issn.1000-8179.20131591 URL |
[20] |
李华, 梁博文, 卜建玲 , 等. 肺结核合并肺癌156例临床分析. 中国防痨杂志, 2013,35(4):268-272.
doi: 10.3969/j.issn.1009-4393.2012.5.030 URL |
[21] |
Lee HY, Choi YL, Lee KS , et al. Pure ground-glass opacity neoplastic lung nodules: histopathology, imaging, and mana-gement. AJR Am J Roentgenol, 2014,202(3):W224-233.
doi: 10.2214/AJR.13.11819 URL |
[22] |
Sugano M, Shimizu K, Nakano T , et al. Correlation between computed tomography findings and epidermal growth factor receptor and KRAS gene mutations in patients with pulmonary adenocarcinoma. Oncol Rep, 2011,26(5):1205-1211.
doi: 10.3892/or.2011.1412 URL pmid: 21811765 |
[23] |
Chung JH, Choe G, Jheon S , et al. Epidermal growth factor receptor mutation and pathologic-radiologic correlation between multiple lung nodules with ground-glass opacity differentiates multicentric origin from intrapulmonary spread. J Thorac Oncol, 2009,4(12):1490-1495.
doi: 10.1097/JTO.0b013e3181bc9731 URL pmid: 19844187 |
[1] | Tuberculosis Control Branch of Chinese Antituberculosis Association, The Youth Branch of Chinese Antituberculosis Association, Editorial Board of Chinese Journal of Antituberculosis. Evidence-based guidelines for application of digital adherence technology in tuberculosis medication management in China [J]. Chinese Journal of Antituberculosis, 2025, 47(4): 385-397. |
[2] | Li Jinhao, Hu Dongmei, Xu Caihong. Investigation on the willingness of tuberculosis health-care workers to implement tuberculosis preventive treatment and analysis of influencing factors [J]. Chinese Journal of Antituberculosis, 2025, 47(4): 398-407. |
[3] | Li Yuhong, Mei Jinzhou, Su Wei, Ruan Yunzhou, Liu Yushu, Zhao Yanlin, Liu Xiaoqiu. Analysis of the treatment outcomes and influencing factors of rifampicin-resistant pulmonary tuberculosis patients aged 65 and above in China from 2015 to 2021 [J]. Chinese Journal of Antituberculosis, 2025, 47(4): 408-415. |
[4] | Jiang Xue, Bai Yunlong, Ma Jianjun, An Yuan, Yang Fan, Zhao Qinglong. Status and influencing factors of diagnosis and treatment delay of rifampicin resistant pulmonary tuberculosis patients, Jilin Province, 2020—2023 [J]. Chinese Journal of Antituberculosis, 2025, 47(4): 416-424. |
[5] | Wu Xuan, Zhang Yanqiu, Xu Jiying, Meng Dan, Sun Dingyong. Analysis of factors influencing the treatment outcomes of patients with pulmonary tuberculosis and diabetes mellitus in Henan Province (2019—2023) [J]. Chinese Journal of Antituberculosis, 2025, 47(4): 425-431. |
[6] | An Yuan, Bai Yunlong, Zhao Qinglong, Ma Jianjun, Jiang Xue, Pan Yan, Gao Ying, Gao Zhihui. Analysis of treatment outcomes and influencing factors of patients with pulmonary tuberculosis complicated with diabetes mellitus in Jilin Province,2018—2022 [J]. Chinese Journal of Antituberculosis, 2025, 47(4): 432-438. |
[7] | Feng Wei, Zheng Hailun, Meng Weili, Luo Ping. Analysis of under-reporting before arrival of pulmonary tuberculosis patients registered and managed by Tuberculosis Prevention and Control Institutions in Xicheng District, Beijing from 2018 to 2023 [J]. Chinese Journal of Antituberculosis, 2025, 47(4): 439-443. |
[8] | Hu Yifan, Du Boping, Wu Yadong, Zhu Chuanzhi, Zhang Lanyue, Jia Hongyan, Sun Qi, Pan Liping, Zhang Zongde, Li Zihui. Experimental study on the role of Mce4C in the uptake and utilization of cholesterol by Mycobacterium tuberculosis [J]. Chinese Journal of Antituberculosis, 2025, 47(4): 444-453. |
[9] | Sheng Jie, Hong Kaifeng, Mierzhati Aisha, Tang Wei, Dilixiati Abulizi. Study on the mechanism of IL-22 and p38 MAPK signaling pathways in inhibiting bone destruction in bone and joint tuberculosis [J]. Chinese Journal of Antituberculosis, 2025, 47(4): 454-459. |
[10] | Wang Yingchao, Liu Weiyi, Ji Xiuxiu, Shang Xuetian, Jia Hongyan, Zhang Lanyue, Sun Qi, Du Boping, Zhu Chuanzhi, Pan Liping, Zhang Zongde. Profile analysis of circRNA expression and identification of diagnostic markers in peripheral blood mononuclear cells of tuberculosis patients [J]. Chinese Journal of Antituberculosis, 2025, 47(4): 460-470. |
[11] | Zhu Mingzhi, Shao Yanqin, Fan Dapeng, Liu Libin, Mei Bin, Dai Lingshan, Cai Long. Diagnostic value of urine lipoarabinomannan antigen detection in extrapulmonary tuberculosis [J]. Chinese Journal of Antituberculosis, 2025, 47(4): 471-476. |
[12] | Hao Mingxiao, Mi Jie, Xu Zongyi. Effectiveness of a continuity of care model in patients with tuberculous meningitis [J]. Chinese Journal of Antituberculosis, 2025, 47(4): 477-481. |
[13] | Shang Xiyu, Zhang Huifang, Cao Yuqing, Xiong Yibai, Ji Xinyu, Tian Yaxin, Li Jiajia, Wang Ni, Ma Yan. Bibliometric analysis of global research status and hotspots in the basic research of Traditional Chinese Medicine for tuberculosis [J]. Chinese Journal of Antituberculosis, 2025, 47(4): 482-497. |
[14] | Qin Lili, Yang Chengqing, Mai Hongzhen, Xu Qifeng, Xue Xinying, Lu Xiwei. Advances in the clinical diagnosis and treatment of post-tuberculosis chronic pulmonary aspergillosis [J]. Chinese Journal of Antituberculosis, 2025, 47(4): 498-504. |
[15] | Luo Li, Luo Linzi, Yin Quhua, Zhou Lei, Lu Zhibin, Ding Yan, Xiao Yangbao. Progress in bronchoscopic diagnosis and treatment of lymph node fistula tracheobronchial tuberculosis [J]. Chinese Journal of Antituberculosis, 2025, 47(4): 505-512. |
Viewed | ||||||
Full text |
|
|||||
Abstract |
|
|||||