Chinese Journal of Antituberculosis ›› 2018, Vol. 40 ›› Issue (9): 924-931.doi: 10.3969/j.issn.1000-6621.2018.09.004
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Xue QI,Ya-cui WANG,Ya-jie GUO,Qi MA,Yu-ying CHEN,Lin SUN(),A-dong SHEN(
)
Received:
2018-07-16
Online:
2018-09-10
Published:
2018-10-17
Contact:
Lin SUN,A-dong SHEN
E-mail:chinatka@163.com;shenad16@hotmail.com
Xue QI,Ya-cui WANG,Ya-jie GUO,Qi MA,Yu-ying CHEN,Lin SUN,A-dong SHEN. Analysis of the results of two detection methods for screening latent tuberculosis infection in children with different risk levels[J]. Chinese Journal of Antituberculosis, 2018, 40(9): 924-931. doi: 10.3969/j.issn.1000-6621.2018.09.004
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因素 | 合计 (483例) | 危险因素等级 | χ2值d | P值d | ||
---|---|---|---|---|---|---|
Ⅲ级a(55例) | Ⅱ 级(210例) | Ⅰ级(218例) | ||||
性别 | 0.296 | 0.863 | ||||
男 | 286(59.21) | 33(60.00) | 121(57.62) | 131(60.09) | ||
女 | 197(40.79) | 22(40.00) | 89(42.38) | 87(39.91) | ||
年龄(岁) | 239.305 | 0.000 | ||||
<5 | 175(36.23) | 48(87.27) | 127(60.48) | 0(0.00) | ||
≥5 | 308(63.77) | 7(12.73) | 83(39.52) | 218(100.00) | ||
BCG接种情况 | 55.952 | 0.000 | ||||
有卡痕 | 457(94.62) | 41(74.55) | 198(94.29) | 218(100.00) | ||
无卡痕 | 26(5.38) | 14(25.45) | 12(5.71) | 0(0.00) | ||
与结核病患者接触程度 | 202.685 | 0.000 | ||||
非密切 | 363(75.16) | 6(10.91) | 139(66.19) | 218(100.00) | ||
密切 | 120(24.84) | 49(89.09) | 71(33.81) | 0(0.00) | ||
居住地地域分布b | 9.532 | 0.049 | ||||
东部 | 283(58.59) | 34(61.82) | 128(60.95) | 121(55.51) | ||
中部 | 121(25.05) | 14(25.45) | 40(19.05) | 67(30.73) | ||
西部 | 79(16.36) | 7(12.73) | 42(20.00) | 30(13.76) | ||
并发疾病 | 41.628 | 0.000 | ||||
呼吸道感染 | 237(49.07) | 31(56.36) | 112(53.33) | 94(43.12) | ||
风湿免疫疾病 | 105(21.74) | 2(3.64) | 32(15.24) | 71(32.57) | ||
血液肿瘤疾病 | 40(8.28) | 7(12.73) | 24(11.43) | 9(4.13) | ||
肾脏疾病 | 32(6.63) | 3(5.45) | 10(4.76) | 19(8.71) | ||
其他c | 69(14.28) | 12(21.82) | 32(15.24) | 25(11.47) | ||
免疫抑制剂治疗 | 0.670 | 0.715 | ||||
否 | 435(90.06) | 48(87.27) | 191(90.95) | 196(89.91) | ||
是(且≥1个月) | 48(9.94) | 7(12.73) | 19(9.05) | 22(10.09) |
危险因 素等级 | TST | IGRA | TST+IGRA任一阳性 | χ2值a | P值a | ||||||
---|---|---|---|---|---|---|---|---|---|---|---|
总数 (例) | 阳性 (例) | 阳性率 (%) | 总数 (例) | 阳性 (例) | 阳性率 (%) | 总数 (例) | 阳性 (例) | 阳性率 (%) | |||
Ⅰ级 | 171 | 16 | 9.36 | 218 | 5 | 2.29 | 218 | 16 | 7.34 | 7.861 | 0.020 |
Ⅱ级 | 157 | 20 | 12.74 | 210 | 5 | 2.38 | 210 | 20 | 9.52 | 13.318 | 0.001 |
Ⅲ级 | 41 | 6 | 14.63 | 55 | 2 | 3.64 | 55 | 8 | 14.55 | 3.456 | 0.178 |
合计 | 369 | 42 | 11.38 | 483 | 12 | 2.48 | 483 | 44 | 9.11 | - | - |
χ2值 | 1.412 | 0.459 | 2.832 | ||||||||
P值 | 0.494 | 0.795 | 0.243 |
临床特征 | IGRA检测 | TST检测 | ||||||
---|---|---|---|---|---|---|---|---|
阳性结果 | χ2值 | P值 | OR(95%CI)值 | 阳性结果 | χ2值 | P值 | OR(95%CI)值 | |
性别 | 2.918 | 0.088 | 0.837 | 0.360 | ||||
男 | 3.50(10/286) | 1.000 | 12.61(28/222) | 1.000 | ||||
女 | 1.02(2/197) | 0.285 (0.062~1.318) | 9.52(14/147) | 0.729 (0.370~1.437) | ||||
年龄(岁) | 2.042 | 0.316 | 0.149 | 0.699 | ||||
<5 | 1.14(2/175) | 1.000 | 10.48(13/124) | 1.000 | ||||
≥5 | 3.25(10/308) | 2.907 (0.629~13.439) | 11.84(29/245) | 1.146 (0.573~2.293) | ||||
居住地地域分布 | 2.466 | 0.347 | 4.147 | 0.126 | ||||
东部 | 1.77(5/283) | 1.000 | 9.13(20/219) | 1.000 | ||||
中部 | 2.48(3/121) | 1.235 (0.290~5.252) | 11.90(10/84) | 1.345 (0.601~3.006) | ||||
西部 | 5.06(4/79) | 2.806 (0.734~10.725) | 18.18(12/66) | 2.211 (1.017~4.806) | ||||
出院诊断 | 0.388 | 0.983 | 9.063 | 0.065 | ||||
呼吸道感染 | 2.11(5/237) | 1.000 | 7.11(14/197) | 1.000 | ||||
风湿免疫疾病 | 2.86(3/105) | 1.456 (0.341~6.223) | 16.25(13/80) | 2.536 (1.134~5.673) | ||||
恶性肿瘤 | 2.50(1/40) | 1.309 (0.148~11.558) | 15.79(3/19) | 2.451 (0.637~9.431) | ||||
肾脏疾病 | 3.13(1/32) | 1.543 (0.174~13.687) | 9.52(2/21) | 1.376 (0.291~6.516) | ||||
其他a | 2.90(2/69) | 0.598 (0.074~4.839) | 19.23(10/52) | 3.112 (1.293~7.489) | ||||
BCG接种情况 | 0.238 | 0.626 | 0.968 | 0.325 | ||||
卡痕阴性 | 3.85(1/26) | 1.000 | 4.76(1/21) | 1.000 | ||||
卡痕阳性 | 2.41(11/457) | 0.598 (0.074~4.839) | 11.78(41/348) | 2.671 (0.349~20.432) | ||||
接受免疫抑制剂治疗 | 0.015 | 0.903 | 0.693 | 0.405 | ||||
否 | 2.53(11/435) | 1.000 | 10.91(36/330) | 1.000 | ||||
是 | 2.08(1/48) | 0.880 (0.111~6.990) | 15.38(6/39) | 1.485 (0.582~3.787) | ||||
接触程度 | 4.291 | 0.038 | 21.131 | <0.05 | ||||
非密切 | 1.65(6/363) | 1.000 | 6.57(18/274) | 1.000 | ||||
密切 | 5.00(6/120) | 3.186 (1.006~10.096) | 25.26(24/95) | 4.329 (2.232~8.396) | ||||
年龄+接触史 | 0.794 | 0.656 | 0.347 | 0.556 | ||||
<5岁+密切 | 2.38(1/42) | 1.000 | 15.63(5/32) | 1.000 | ||||
≥5岁+密切 | 6.41(5/78) | 2.612 (0.294~23.236) | 20.63(13/63) | 1.404 (0.452~4.358) | ||||
卡痕+接触史 | 1.087 | 0.297 | 1.767 | 0.184 | ||||
阴性+密切 | 12.50(1/8) | 1.000 | 0.00(0/7) | 1.000 | ||||
阳性+密切 | 4.46(5/112) | 0.313 (0.031~3.117) | 23.38(18/88) | 1.257 (1.131~1.398) |
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