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中国防痨杂志 ›› 2026, Vol. 48 ›› Issue (8): 1199-1204.doi: 10.19982/j.issn.1000-6621.20250529

• 论著 • 上一篇    下一篇

置管引流辅助治疗26例胸椎结核并发椎旁脓肿疗效分析

范俊(), 董伟杰, 唐恺, 李元, 严广璇, 王恒, 朱乾坤, 李永超, 兰汀隆   

  1. 首都医科大学附属北京胸科医院骨科/北京市结核病胸部肿瘤研究所, 北京 101149
  • 收稿日期:2025-12-27 出版日期:2026-08-01 发布日期:2026-07-30
  • 通信作者: 范俊,Email: fanjun4981@163.com

Analysis of the therapeutic effect of 26 cases of thoracic tuberculosis and paravertebral abscess with tube drainage assistance

Fan Jun(), Dong Weijie, Tang Kai, Li Yuan, Yan Guangxuan, Wang Heng, Zhu Qiankun, Li Yongchao, Lan Tinglong   

  1. Department of Orthopaedics, Beijing Chest Hospital, Capital Medical University, Beijing Tuberculosis and Tumor Research Institute, Beijing 101149, China
  • Received:2025-12-27 Online:2026-08-01 Published:2026-07-30
  • Contact: Fan Jun,Email: fanjun4981@163.com

摘要:

目的: 探讨CT引导下置管引流辅助治疗胸椎结核并发椎旁脓肿的临床疗效与安全性。方法: 回顾性分析2020年1月至2024年7月首都医科大学附属北京胸科医院骨科收治的26例胸椎结核并发椎旁脓肿患者的临床资料。所有患者均在CT引导下于局部麻醉下行置管引流术。记录手术时间、出血量、引流量及引流时间,比较术前与术后体温、视觉模拟评分(visual analogue scale,VAS)、血红细胞沉降率(erythrocyte sedimentation rate,ESR)及C反应蛋白(C-reactive protein,CRP)水平变化,并随访12~24个月。结果: 26例患者均顺利完成置管引流,平均引流时间为(4.8±2.3)d,总引流量为50~200ml。ESR由术前的(49.8±20.4)mm/1h降至术后的(19.4±10.2)mm/1h,CRP由术前的(20.9±9.6)mg/L降至术后的(8.6±3.6)mg/L,VAS评分由术前的(7.5±1.8)分降至术后的(2.4±1.6)分,差异均有统计学意义(t值分别为3.464、3.492和3.650;P值均<0.001)。未发生大血管损伤、神经损伤及窦道形成等严重并发症。末次随访时,未见后凸畸形导致的疼痛或者神经功能障碍。结论: CT引导下置管引流治疗胸椎结核并发椎旁脓肿安全、微创且有效,同时进行抗结核治疗,可减轻脓肿对周围组织的进一步侵袭,改善ESR、CRP等炎症指标,进而改善患者的结核中毒症状,并有助于降低后续手术创伤风险,适用于全身状况较差或不能耐受开胸手术的患者,具有一定的临床应用价值。

关键词: 结核,脊柱, 胸椎, 脓肿, 引流术, 外科手术, 微创性

Abstract:

Objective: To evaluate the clinical efficacy and safety of CT-guided catheter drainage as an adjunctive treatment for thoracic spinal tuberculosis with paravertebral abscess. Methods: A retrospective analysis was conducted on 26 patients with thoracic spinal tuberculosis complicated by paravertebral abscess who were treated in the Department of Orthopedics, Beijing Chest Hospital, Capital Medical University, between January 2020 and July 2024. All patients underwent CT-guided catheter drainage under local anesthesia. Operative time, blood loss, drainage volume, and duration of drainage were recorded. Preoperative and postoperative body temperature, visual analogue scale (VAS) score, erythrocyte sedimentation rate (ESR), and C-reactive protein (CRP) levels were compared. All patients were followed up for 12-24 months. Results: All 26 patients successfully underwent catheter drainage. The mean drainage duration was (4.8±2.3) days, and the total drainage volume ranged from 50 to 200 ml. The ESR decreased from a preoperative level of (49.8±20.4) mm/1 h to a postoperative level of (19.4±10.2) mm/1 h; CRP levels decreased from (20.9±9.6) mg/L preoperatively to (8.6±3.6) mg/L postoperatively; and the VAS score decreased from (7.5±1.8) preoperatively to (2.4±1.6) postoperatively, with all differences being statistically significant (t=3.464, 3.492, and 3.650, respectively; all P<0.001). No serious complications, such as major vascular injury, nerve injury, or sinus tract formation, were observed. During follow-up, all abscesses resolved, the extent of vertebral inflammation decreased, and no recurrence was observed. Conclusion: CT-guided catheter drainage is a safe, minimally invasive, and effective treatment for thoracic spinal tuberculosis with paravertebral abscess. It can reduce abscess burden, improve inflammatory markers and clinical symptoms, and may help decrease the invasiveness of subsequent surgical procedures. This technique is particularly suitable for patients in poor general condition or those who cannot tolerate thoracotomy, and has promising clinical application value.

Key words: Tuberculosis, spinal, Thoracic spine, Abscess, Drainage, Surgical procedures, minimally invasive

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