Abstract:

Cells can release their own substances or metabolites outside the cell through extracellular vesicles, which is also known as EV (exosomes). As research progressed, it is discovered that bacteria can also produce exosomes that encapsulate many macromolecules (including proteins, lipids, DNA and RNA) and that bacterial exosomes are closely linked to a variety of biological activities, including bacterial survival and development, as well as bacterial-mediated intra- and inter-species interactions. Researchers have also found that both Gram-negative and Gram-positive bacteria can produce exosomes containing DNA, and that bacterial exosomes DNA can perform biological functions such as mediating horizontal gene transfer, assisting in biofilm formation, and stimulating immunomodulatory mechanisms. In this paper, the production mode and biological functions of bacterial extracellular DNA have been elucidated, so that readers can have deeper understanding of bacterial exosomes DNA and promote further research and development of bacterial exosome DNA.

Key words: Extracellular vesicles, Deoxyribonucleotides, Gram-negative bacteria, Gram-positive bacteria, Consensus development conferences as topic