Mycobacterium tuberculosis; drug-resistance; bacterial; microbial sensitivity tests; rifampin; isoniazid;

Abstract

Abstract: Objective To evaluate the effect of MTBDRplus assay in rapid detection of resistance to rifampin(RIF) and isoniazid(INH) in Mycobacterium tuberculosis clinical isolates collected in Beijing.Methods A total of 169 clinical isolates were enrolled in the study.Using the tranditional drug susceptibility testing as the control,the sensitivity and specificity of the MTBDRplus assay and the variety of gene mutations were assessed.Results The sensitivity and specificity of MTBDRplus assay for the detection of RIF a...

Key words: Mycobacterium tuberculosis, drug-resistance, bacterial, microbial sensitivity tests, rifampin, isoniazid

CLC Number:

R446.5

JIAN Ji-Yong, WANG Nen-Han, YI Jun-Li, XING Qing, LIU Xiao-Xue, WANG Su-Min, HONG Feng. Mycobacterium tuberculosis; drug-resistance; bacterial; microbial sensitivity tests; rifampin; isoniazid;[J]. Chinese Journal of Antituberculosis, 2010, 32(10): 9-12.

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Mycobacterium tuberculosis; drug-resistance; bacterial; microbial sensitivity tests; rifampin; isoniazid;

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