Abstract: bjective To analyse the antituberculosis_drug resistance and chemotherapy of sputum culture_positive in 122 cases with recurrent pulmonary tuberculosis(RPT).Methods Drug_susceptibility tests was done in sputum culture_positive cases with RPT between 1995 and 1997.HREZ/HRE was used as therapeutic scheme.Sputum examination for tubercle bacillus was performed three times at least.Results The sputum negative conversion rates at the end of the chemotherapy in the drug_susceptible group(91 cases)and the drug_resistant group(31 cases)were 85.7% and 67.7%,respectively.Conclusions If the drug_resistance,particularly for multidrug_resistant,occurred in recurrent cases during retreatment,the therapeutic efficacy is less satisfactory than that in the drug_susceptible cases.It is important to control the infectious source of new treated cases actively and reduce occurrence of drug_resistant cases for tuberculosis control project.

Key words: Tuberculosis, pulmonary, Relapse, Treatment