Chinese Journal of Antituberculosis ›› 2024, Vol. 46 ›› Issue (7): 845-848.doi: 10.19982/j.issn.1000-6621.20240105
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Received:2024-03-21
Online:2024-07-10
Published:2024-07-01
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| 患者 | 单分泌 IFN-γ | 单分泌 IL-2 | 单分泌 TNF-α | 双分泌 IFN-γ/IL-2 | 双分泌 IFN-γ/TNF-α | 双分泌 IL-2/TNFα | 三分泌IFN-γ/ IL-2/TNF-α |
|---|---|---|---|---|---|---|---|
| 病例1 | |||||||
| T细胞频数(SFCs/250000PBMC) | 149 | 24 | 21 | 56 | 31 | 23 | 62 |
| T细胞比例(%) | 41 | 7 | 6 | 15 | 8 | 6 | 17 |
| 病例2 | |||||||
| T细胞频数(SFCs/250000PBMC) | 44 | 9 | 5 | 4 | 0 | 1 | 0 |
| T细胞比例(%) | 70 | 14 | 8 | 6 | 0 | 2 | 0 |
| [1] | Pang Y, An J, Shu W, et al. Epidemiology of Extrapulmonary Tuberculosis among Inpatients, China, 2008—2017. Emerg Infect Dis, 2019, 25(3): 457-464. doi:10.3201/eid2503.180572. |
| [2] | World Health Organization. Latent tuberculosis infection: updated and consolidated guidelines for programmatic management. Geneva: World Health Organization, 2018. |
| [3] | Gong W, Wang P, Xiong X, et al. Chloroform-Methanol Residue of Coxiella burnetii Markedly Potentiated the Specific Immunoprotection Elicited by a Recombinant Protein Fragment rOmpB-4 Derived from Outer Membrane Protein B of Rickettsia rickettsii in C3H/HeN Mice. PLoS One, 2015, 10(4): e0124664. doi:10.1371/journal.pone.0124664. |
| [4] | Liang Y, Zhang X, Xiao L, et al. Immunogenicity and therapeutic effects of pVAX1-rv1419 DNA from Mycobacterium tuberculosis. Curr Gene Ther, 2016 [2024-03-20]. Online ahead of print. |
| [5] |
Halliday A, Whitworth H, Kottoor SH, et al. Stratification of Latent Mycobacterium tuberculosis Infection by Cellular Immune Profiling. J Infect Dis, 2017, 215(9): 1480-1487. doi:10.1093/infdis/jix107.
pmid: 28329119 |
| [6] | Salgame P, Geadas C, Collins L, et al. Latent tuberculosis infection-Revisiting and revising concepts. Tuberculosis (Edinb), 2015, 95(4): 373-384. doi:10.1016/j.tube.2015.04.003. |
| [7] |
Mayer-Barber KD, Sher A. Cytokine and lipid mediator networks in tuberculosis. Immunol Rev, 2015, 264(1): 264-275. doi:10.1111/imr.12249.
pmid: 25703565 |
| [8] | Sudbury EL, Clifford V, Messina NL, et al. Mycobacterium tuberculosis-specific cytokine biomarkers to differentiate active TB and LTBI: A systematic review. J Tnfect, 2020, 81(6): 873-881. doi:10.1016/j.jinf.2020.09.032. |
| [9] |
Zhang L, Wan S, Ye S, et al. Application of IFN-γ/IL-2 FluoroSpot assay for distinguishing active tuberculosis from non-active tuberculosis: A cohort study. Clin Chim Acta, 2019, 499: 64-69. doi:10.1016/j.cca.2019.08.022.
pmid: 31454491 |
| [10] |
Kim JY, Park JH, Kim MC, et al. Combined IFN-γ and TNF-α release assay for differentiating active tuberculosis from latent tuberculosis infection. J Infect, 2018, 77(4): 314-320. doi:10.1016/j.jinf.2018.04.011.
pmid: 29746954 |
| [11] | Zhang L, Wan S, Zhou Z, et al. Utility of interferon gamma/tumor necrosis factor alpha FluoroSpot assay in differentiation between active tuberculosis and latent tuberculosis infection: a pilot study. BMC Infect Dis, 2021, 21(1): 651. doi:10.1186/s12879-021-06351-w. |
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