Abstract:

To investigate the clinical features and prognosis of the pregnant or parturient women with severe tuberculosis, the clinical data of 30 patients (21 pregnant women and 9 parturients) with severe tuberculosis admitted to the tuberculosis department of the Urban Public Health Clinical Medical Center from January 2013 to June 2018 were collected and analyzed in this study. The results showed that the symptoms of patients were fever (90.0%, 27/30), shortness of breath (86.7%, 26/30), and cough (76.7%, 23/30). Hematogenous pulmonary tuberculosis was the most common form (73.3%, 22/30) of tuberculosis, and 33.3% (10/30) of the patients were complicated with extrapulmonary tuberculosis. Of the 30 patients, 11 (36.7%) patients underwent in vitro fertilization-embryo transfer (IVF-ET); 4 patients died in the hospital, 2 patients died by phone follow-up after being discharged; 9 parturients gave birth to live babies outside the hospital, 14 cases of pregnant women induced labor or abortion, 4 cases of pregnant women delivered successfully in our hospital, and 3 cases of pregnant women continued pregnancy. In conclusion, the pregnant or parturient women in severe tuberculosis are lack of typical clinical manifestations, mainly with hematogenous pulmonary tuberculosis. Timely diagnosis and standardized treatment should be made to improve the prognosis. Meanwhile, tuberculosis screening is recommended for women who plan to undergo IVF-ET.

Key words: Tuberculosis, pulmonary, Pregnant women, Critical care, Signs and symptoms, Prognosis, Data interpretation, statistical