Abstract:

The clinical data of 12 patients with cervical lymph node tuberculosis (CTL) complicated with AIDS who underwent surgical treatment were collected in the Infectious Diseases Hospital Affiliated to Soochow University from April 2012 to June 2018. There were 10 males and 2 females; They were 19-62(38.0±11.3)years old. Both the standard anti-tuberculosis and antiviral drugs were supplemented by surgical treatment, and the level of CD4 ⁺ T lymphocytes, the ratio of CD4 ⁺ T lymphocytes/CD8 ⁺ T lymphocytes and the rate of blood cell deposition (ESR) were compared and analyzed before and 3 months after operation. CD4 ⁺ T lymphocyte were (267.07±77.89)cells/μl after operation, preoperative level were (156.80±84.83)cells/μl, the ratio of CD4 ⁺/CD8 ⁺ T lymphocyte was 0.68±0.53, preoperative ratio was 0.47±0.32. The differences were statistically significant (t=28.30, P=0.019; t=20.37, P=0.033). The postoperative ESR was (15.88±11.08) mm/1 h, and the preoperative ESR was (52.32±17.12) mm/1 h. The difference was statistically significant (t=12.92, P=0.025). All the 12 patients were followed up, 11 patients had primary wound healing and CTL symptoms disappeared; 1 case had delayed wound healing and healed after 2 months of local dressing change; 3 cases had recurrence of CTL, and the wound healed well after operation; 1 case died in the course of treatment, the cause of death was late AIDS and complicated with refractory pneumocystis pneumonia. Normalized control of anti-tuberculosis and antiviral drugs, combined with reasonable and precise surgical intervention at appropriate time, has a better therapeutic effect on patients with cervical lymph node tuberculosis complicated with AIDS.

Key words: Tuberculosis, lymph node, Acquired immunodeficiency syndrome, Comorbidity, Lymph node excision, Drug therapy, combination, Treatment outcome