Abstract: Objective To evaluate the implementation effect and the achievements of the objectives of Shenzhen tuberculosis control and prevention programme from 2001 to 2010，and to provide scientific recommendations for sustainable development of TB control. Methods The data from TB reporting system and TB Control and Prevention Programme final evaluation between 2001 to 2010 were collected, SPSS 13.0 was applied to analyze the financial investment、human resources and DOT coverage rate, referral and tracing situation of 195 201 TB suspects from 2005—2010, as well as the detection、treatment and management situation of 34 024 TB patients, and the epidemiology situation and social and economic benefits from 2001 to 2010. Results (1)Shenzhen implemented DOT strategy for the entire region，all people and all types of patients, the coverage rate reached 100.00%（660/660）.(2)The number of TB control staff in 2010 were 152, which was increased by 70.79%(63/89), 55.26% (84/152) of the staff had bachelor degree or above.(3) The overall arrival rate of the suspects among floating population was significantly lower than the resident population during 2005—2010, which were 69.21% (127 583/184 334) and 99.03% (10 762/10 867) respectively (χ²=4420.76，P＜0.01). (4) A total of 34 024 active pulmonary tuberculosis cases were detected from 2001 to 2010, among which 22 008 were smear positive cases and 12 016 were smear negative cases. The average cure rate of smear positive cases was 85.36% (18 787/22 008), and the average treatment success rate was 89.03% (30 292/34 024). The average cure rate and treatment success rate of the floating patients were 82.91%(14 479/17 463) and 87.25%(23 290/26 693), which was significantly lower than the resident patients (94.79%(4308/4545), 95.51%(7002/7331)) (χ²=406.92，401.91，P＜0.01). (5) The prevalence rate of smear positive of resident population was 19.44 per 100 000 population, which decreased 70.55% (46.56/66.00) compared with that of 2000, and that of the floating population was 59.96 per 100 000 population, which decreased 27.23% (22.44/82.40) compared with that of 2000.(6) About 0.15 billion yuan was invested in TB control from 2001 to 2010, 136 700 healthy people were protected from TB infection and 13 700 people were prevented to be new TB cases, the direct and indirect social and economic benefits reached 20.245 billion yuan. For every 1 yuan input into the TB control, 134.98 yuan of social and economic benefits can be produced. Conclusion Shenzhen has made substantial progress to control TB, while there are still some new challenges to be faced during the implementation of the Twelfth Five-year Plan.

Key words: Tuberculosis, pulmonary/prevention &, control, Health plan implementation, Cost-benefit analysis, Evaluation studies, Shenzhen city