Abstract: Objective To determine the effect of bronchofiberscope and catheter intervention combined with chemotherapy in the treatment of endobronchial tuberculosis.Methods To divide the patients with endobronchial tuberculosis diagnosed by bronchoscope.Sputum smere and clinical manifestation into two groups.One group was treated by bronchofiberscope and catheter intervention combined with chemotherapy,the other was treated simply by chemotherapy.Results The improvement rate of clinical symptoms.Radiographic and bronchoscopic manifestations and bacilli negative convertion rate in combined therapy group were significantly higher than that in simple therapy group (P＜0.01,P＜0.05).And after 6 months’ therapy,bronchoscopic improvement and negative convertion rate in the combined therapy group were significantly higher than that in simple therapy group (P＜0.05).In granulomatous and ulcerative subtypes of tuberculosis,the efficacy rate in comlined therapy group was higher than in simple therapy group.But in exudative and cicatricial subtypes,there was no significant difference in two groups.Conclusion Bronchofiberscope and catheter intervention combined chemotherapy could be applied in granulomatous and ulcerative endobronchial tuberculosis,for the therapy could not only rapidly relieve clinical symptoms,but also auelerate lesion absorbtion and improve treatment effect.

Key words: Eudobronchial, Tuberculosis, Bronchofierscope