Abstract: Objective To determine the status of diagnosis and treatment of drug resistant tuberculosis patients in Shenzhen in order to provide evidences for policy makers on TB control.Methods To investigate drug resistant TB patients from city and county level TB dispensaries and infectious disease hospitals on diagnosis,treatment and management situation in 2002-2003.Results 103 drug resistant TB patients had been diagnosed and treated in 2002—2003.The laboratory method selected for diagnosis was different.28.1% of treatment regimens were irrational,direct observed treatment (DOT) was not provided to patients.The cure rate was 34.9%,the failure rate was 30.1%,the default rate was 13.6%.9.7% of cases were not evaluated.Conclusion Epidemical situation of MDR TB is very severer in the city.It is necessary to establish criteria for diagnosis,treatment and management of MDR TB and implement DOTS PLUS tactics to control the prevalence of MDR TB.

Key words: Pulmonary tuberculosis/prevention and control, Tuberculosis,MDR, Shenzhen City