The social impacts of MDR-TB on patients compared to non-MDR-TB in Henan province

Abstract

Abstract: Objective To investigate the social impacts of MDR-TB and compare to non-MDR-TB in Henan province in 2010 to provide scientific evidence for developing comprehensive TB control strategies. Methods Participants were randomly selected by using Excel generated random digits table from an anti-TB drug resistance surveillance survey dataset collected by the Institute for Tuberculosis Control and Prevention, Henan Centre for Disease Control and Prevention in 2001, supported by the World Health Organization. Face to face interviews were carried out using a questionnaire to collect information on the social impacts among MDR-TB and non-MDR-TB patients. Bivariate analysis was performed for data analysis. Altogether 234 TB cases were interviewed. Among the interviewed cases, 86 were MDR-TB cases and 148 were non-MDR-TB cases based on their anti-TB drug resistance status. T-test was applied in continuous variables and Chi square test was used for categorical variables for comparison. Results Compared to non-MDR-TB (52.4%, 77/148), a greater proportion of MDR-TB patients (70.9%, 61/86) reported pessimism (χ²=8.58, P=0.01). More MDR-TB patients (9.3%, 8/86) continued working outside when they were ill with TB compared to non MDR-TB patients (2.0%, 3/148) and the difference was statistically significant (χ²=6.43, P=0.01). However, after TB recovery, less MDR-TB patients (8.8%, 7/80) were able to work outside compared to non-MDR-TB patients (24.0%, 35/146), and the difference between the two groups was statistically significant (χ²=7.92, P<0.01). Compared to non-MDR-TB patients (18.9%, 28/148), more MDR-TB patients (34.9%, 30/86) maintained their smoking habit after they became ill with TB (χ²=7.44, P<0.01). A substantially greater proportion of MDR-TB patients reported future plans changed because of the disease compared to non-MDR-TB patients (45.8%,33/72 vs 23.9%,27/113, χ²=11.67, P<0.01). Conclusion The findings from this study suggest that social support to TB patients, especially MDR-TB patients is an important factor to be concerned when designing a comprehensive TB program.

Key words: Tuberculosis, Drug resistance, bacterial, Quality of life, Henan province

SUN Yan-ni, WANG Guo-jie, ZHEN Xin-an, LIU Zhan-feng, Harley David, Hall Gillian, Vally Hassan, Sleigh Adrian. The social impacts of MDR-TB on patients compared to non-MDR-TB in Henan province[J]. Chinese Journal of Antituberculosis, 2013, 35(1): 41-47.

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