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Chinese Journal of Antituberculosis ›› 2012, Vol. 34 ›› Issue (9): 585-591.

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Systematic review and implemention progress of DOTS strategy

CHENG Shi-ming, LIU Er-yong, WANG Fang, MA Yan, ZHOU Lin, WANG Li-xia, WAN Li-ya   

  1. National Center for Tuberculosis Control and Prevention, Chinese Center for Disease Control and Prevention,Beijing 102206,China
  • Received:2012-05-16 Online:2012-09-10 Published:2012-12-17
  • Contact: CHENG Shi-ming

Abstract: Objective  To describe and review the implementation progress of DOTS strategy.  Methods  Through discussion with the invited experts, we determined the key words of retrival literature, and searched 12 database, 4 health agencies websites and Google Scholar. A total of 2182 papers between 1990—2010 were searched out including papers describing or evaluating DOTS strategy, cost-effectiveness analysis, experience on prevention and control.  Results  Of the 26 studies included in the analysis, 11 studies were WHO annual reports, 10 studies aimed to describe and evaluate DOTS strategy, 5 studies aimed to evaluate the effectiveness of DOTS strategy; the implementation of the DOTS strategy raised the cure rates by 13.1%-92.1%,the treatment success rate increased to 92.4%-95.0%, the registration rate increased by 163.0%-217.8%; prevalence rate and the loss rate decreased by 30.0%-50.0% and 73.0%-52.6% respectively. In addition, implementation of the DOTS strategy improved the cost-effectiveness as well. Conclusion  The strong government commitment is prerequisite for sustainable implementation of the strategy, effective implementation of the DOTS strategy put the TB under control, meanwhile has a good cost-effectiveness.

Key words: Tuberculosis/prevention &, control, Health plan implementation, Cost-benefit analysis, Evaluation studies