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Chinese Journal of Antituberculosis ›› 2012, Vol. 34 ›› Issue (12): 768-772.

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The analysis of anti-TB treatment outcome of different institutional sources of HIV-positive TB patients

LAI Yu-ji,CHENG Shi-ming,ZHOU Lin,LIU Er-yong,WANG Dong-mei,Li Tao   

  1. Center for Tuberculosis Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 102206, China
  • Received:2012-10-19 Online:2012-12-10 Published:2013-03-09
  • Contact: CHENG Shi-ming E-mail:smcheng@chinatb.org

Abstract: Objective  To compare the characteristices and anti-TB treatment outcome of HIV-positive TB patients from TB programme and AIDS programme. Methods  We collected the TB-related information from TB information management system and HIV-related information from HIV institutions. In the selected fouteen counties within six provinces, a total of 925 TB/HIV cases were registered between Spe.2007 and Aug.2009, 673(72.8%) were known to be HIV positive and referred by HIV institutions and 252(27.2%) were newly detected HIV positive cased by TB institutions.  Results  In areas where HIV transmited mainly through illegal blood donation, the treatment success rate was 90.6%(328/362)and 82.4%(70/85)(χ2=4.806,P =0.034)and the death rate was 7.5%(27/362)and 16.5%(14/85)(χ2=6.711,P=0.010)repsectively for TB/HIV patients from HIV institutions and TB institutions. In areas where HIV transmited mainly through drug use and sex, the treatment success rate was 60.1%(187/311)and 68.9%(115/167)(χ2=3.563,P =0.059)and the incidence of adverse drug response was 24.1%(75/311) and 13.8%(23/167)(χ2=7.132,P =0.009)repsectively for TB/HIV patients from HIV institutions and TB institutions.  Conclusion  We should intensify TB case finding in people living with HIV/AIDS. Meanwhile, HIV testing in TB patient is also an important measure.

Key words: Tuberculosis, pulmonary/drug therapy, Treatment outcome, HIV infections, Superinfection