Abstract: Objective To investigate the HIV infection situation among TB patients in Guangdong province and to analyze its epidemiological characteristics. Methods This is a cross-sectional design.New registered patients registered from September 2008 to January 2009 in 30 counties were investigated by questionnaire and tested for HIV infection.Results 5447 TB cases were investigated,of which 25 cases were found HIV-positive.The HIV infection rate was 0.46%（95%CI:0.28%—0.64%）.The HIV infection rate among TB patients in Western Guangdong was 1.28%（95%CI:0.67%—1.88%）which is higher than the average rate of the whole province,and also higher than Middle and Eastern Guangdong（P<0.01）.For age distribution,the HIV infection rate was highest of 0.85% in TB patients between 30 to 50 years old（χ²=8.883,P=0.012）.The HIV infection rate among TB patients in household population was higher than the floating population（χ²=4.624,P=0.032）.Conclusion The overall HIV infection among TB patients was at a low level in Guangdong,but high in part areas.It is necessary to implement TB/HIV prevention and control in the area with high HIV/AIDS epidemic and/or high TB/HIV co-infection rate.

Key words: Tuberculosis, HIV infections, Superinfection, Questionnaires, Guangdong province